Advances in basic research have yielded a lot of new knowledge and hypotheses based largely on the study of human cell lines and animal models. To translate some of this knowledge into clinically useful markers and targets for cancer therapy, it is important to improve the availability of human tumour tissue to researchers.
Sunnybrook Research Institute's tumour bank provides a mechanism for the optimal collection, storage and distribution of human tissue for investigative purposes. We collect both freshly frozen and formalin-fixed paraffin-embedded tumour and normal samples, retrospectively and prospectively (informed consent and confidential consent is obtained from patients before sample collection).
Our mandate is to design, implement and manage the structures and processes to ensure the timely provision of tissue samples and associated data.
We are currently building bank on four disease sites:
We are also creating and maintaining a database with a tissue tracking and inventory system, using TissueMetrix software.