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Transgenic Core Facility
Sunnybrook Research Institute
Toronto, Ontario, Canada


The transgenic facility (TF) at Sunnybrook Research Institute (SRI) provides the technical expertise, equipment and pathogen-free animal quarters necessary for the production of transgenic mice on a fee-for-service basis.

We offer the following services to the SRI community as well as investigators from external institutions:

  • Rederivation from live mice or frozen embryos
  • Diploid or tetraploid aggregation to generate transgenic mice
  • Cryopreservation of embryos
  • Recovery of mouse lines from cryopreserved embryos
  • Pronuclear injection
  • Other mouse manipulations including surgical procedures and the administration of drugs and other treatment