Magnetic Resonance Imaging
The MRI research group at Sunnybrook is a collaborative collection of scientists dedicated to the improvement of MRI technology and related biophysics for broad applications in health care.
Gait and Sensorimotor Research Laboratory
The gait and sensorimotor research lab is where the group conducts most of testing and data acquisition with stroke patients and normal control volunteers. The lab consists of a variety of sensorimotor neurophysiological equipment including a GaitRite™ Mat, EEG, EMG, and body weight-supported treadmill.
Interventional Biostimulation Laboratory
In the interventional biostimulation laboratory, we will be investigating and conducting biostimulation therapies including use of transcranial magnetic stimulation (TMS) and functional electrical stimulation (FES) and stimulus localization (stereotaxic equipment).
Brain Imaging Laboratory
In the brain imaging laboratory, we are using and further developing advanced imaging acquisition and computational analysis techniques to diagnose, quantify and monitor progression of cerebral vasculopathy and neurodegeneration better. We are also documenting responses to new disease modifying therapies. We are analyzing images obtained from variety of imaging modalities including structural and functional MRI, diffusion tensor imaging, magnetic resonance spectroscopy, magnetization transfer imaging, quantitative T2, PET, SPECT and CT imaging. In conjunction with the LC Campbell Cognitive Neurology Research Unit, the prospective longitudinal Sunnybrook dementia study, funded by CIHR for over 13 years, has become an invaluable resource and archive of standardized, comprehensive clinical-behavioural data and brain images in over one thousand patients. We have developed computational volumetric analysis software and contributed many original observations on relationships between large and small vessel cerebrovascular injury and Alzheimer's disease.
Dr. Thomas and Harriet Black Transient Ischemic Attack Unit
By creating a new model of care for patients with TIA and minor stroke, this unit, due to open in spring 2007, aims to transform stroke prevention, teaching and research at Sunnybrook for those who are at the highest risk for stroke. At Sunnybrook, stroke is already a transformational program within the neurosciences priority program and this unit will enhance the hospital’s role as a provincial and national leader in stroke prevention.
The LC Campbell Cognitive Neurology Research Unit
This unit is dedicated to improving diagnosis and treatment of Alzheimer's disease, vascular and other dementias through optimal utilization of neuroimaging, clinical and neuropsychological tools. In partnership with the brain imaging unit, the focus is on accelerated development of advanced, quantitative imaging techniques to help bring them to the point of care more quickly to improve the lives of patients and families living with these devastating neurodegenerative conditions. Visit their Web site for more information.
Regional Stroke Centre
Sunnybrook is home to one of Ontario’s provincial Regional Stroke Centres, specifically serving the north and east Greater Toronto Area. In addition to its focus on stroke prevention, acute stroke care and stroke rehabilitation and recovery, the existence of the Regional Stroke Centre at Sunnybrook has established a pipeline for patient recruitment, which is an essential requirement for our intended translational research. Supported by funding from the Ministry of Health and Long-Term Care in Ontario, Sunnybrook was selected for its leadership in stroke research and its strategic geographic location in the centre of the city of Toronto.
Secondary Stroke Prevention Clinic
Cognitive Neurology Clinic
Stroke Clinical Trials Research Unit
Through the Stroke Clinical Trials Research Unit, we are actively engaged in contract clinical trials research in acute stroke and stroke prevention. Funding from these industry sponsored trials support clinical nurse coordinators and contributes to stroke outcome research each year.