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SRI Profiles

Victor Yang
Victor Yang

Senior scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room M6 156
Toronto, ON
M4N 3M5

Phone: 416-480-6100, ext. 87576
Fax: 1-888-317-4689

Research Coordinator: June Warenycia
Room: M6 100
Phone: 416-480-6100, ext. 87576
Email: june.warenycia@sunnybrook.ca 

Education:

  • BA.Sc., 1997, engineering science (biomedical), University of Toronto, Canada
  • MA.Sc., 1998, electrical and computer engineering, U of T
  • PhD, 2004, medical biophysics, U of T
  • MD, 2006, faculty of medicine, U of T

Appointments and Affiliations:

  • Senior scientist, Physical Sciences, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute
  • Neurosurgeon, Sunnybrook Health Sciences Centre
  • Associate professor, Institute of Medical Sciences, University of Toronto
  • Associate professor of surgery, faculty of medicine, U of T
  • Associate professor (status), electrical and computer engineering, U of T
  • Associate professor, electrical and computer engineering, Ryerson University
  • Adjunct professor, medical physics, Ryerson University
  • Canada Research Chair in Biophotonics and Bioengineering, Tier 2

Research Foci:

  • Optical coherence tomography
  • Intraoperative fluorescence imaging
  • Micro-machined electromechanical probes and catheters
  • Medical imaging
  • Surgical guidance

Research Summary:

Dr. Yang is well-recognized for his work in advanced fibre-optical probes for imaging tissue microstructure and microcirculation. His work has led to the development of new diagnostic imaging and therapeutic monitoring tools for minimally invasive procedures.

Dr. Yang's research has:

  • improved catheter designs and developed new methods for Doppler optical coherence tomography (OCT) in interstitial, intravascular and endoscopic studies
  • developed speckle variance as a tool for microvasculature detection using swept source OCT
  • developed high power polygon filter-based Frequency Domain Mode Lock (FDML) tunable laser sources for OCT
  • developed Yb-doped fibre gain element for high power multichannel OCT
  • demonstrated multichannel OCT for in vivo imaging
  • used ultra-short pulsed laser ablation in hard tissues for inline coherent imaging
  • developed tools to detect cell death with spectroscopic OCT
  • used artificial muscle actuation for catheter-based OCT imaging 
  • conducted an in vivo preclinical trial of endovascular OCT imaging of carotid artery.

Selected Publications:

See current publications list at PubMed.

See current publications list at Google Scholar.

  1. Sun C, Nolte F, Lee KKC, Cheng KHY, Vuong B, Standish BA, Courtney BK, Marotta TR, Mariampillai A, Yang VXD. In¬ vivo feasibility of endovascular Doppler optical coherence tomography. Biomed Opt Express. 2012 Oct;3(10):2600–10.
  2. Mariampillai A, Standish BA, Moriyama EH, Khurana M, Munce NR, Leung MKK, Jiang J, Cable A, Wilson BC, Vitkin IA, Yang VXD. Speckle variance detection of microvasculature using swept-source optical coherence tomography. Optics Lett. 2008 Jul;33:1530–32.
  3. Yang VXD, Gordon ML, Tang S, Marcon NE, Gardiner G, Qi B, Bisland S, Seng-Yue E, Lo S, Pekar J, Mok A, Wilson BC, Vitkin IA. High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts. Opt Express. 2003 Sep;11(19):2416–24.
  4. Yang VXD, Gordon ML, Qi B, Pekar J, Lo S, Seng-Yue E, Mok A, Wilson BC, and Vitkin IA. High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamics of Xenopus laevis. Opt Express. 2003 Jul;11(14):1650–58.
  5. Yang VXD, Gordon ML, Qi B, Pekar J, Lo S, Seng-Yue E, Mok A, Wilson BC, Vitkin IA. High speed, wide velocity dynamic range Doppler optical coherence tomography (Part I): System design, signal processing and performance. Opt Express. 2003 Apr;11(7):794–809.

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