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SRI Profiles

Pamela Angle, MD, M.Sc.

Associate scientist

Sunnybrook Research Institute,
2075 Bayview Ave.
Toronto, ON M4N 3M5

Phone: 416-480-6100, ext. 87757
Fax: 416-480-5614

Clinical Profile

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Credentials:

  • B.Sc., Biochemistry, Trinity University
  • MD, Harvard University
  • Diplomate, American Board of Anesthesiology
  • Fellow, Royal College of Physicians and Surgeons of Canada
  • M.Sc., health research methodology, McMaster University
  • M.Sc., evidence-based health care programme, Oxford University, UK
  • PhD candidate, evidence-based health care programme, Oxford University, UK

Current Appointments:

  • Associate scientist, evaluative clinical sciences, Women and Babies Research Program, Sunnybrook Research Institute (SR)
  • Director, Obstetrical Anesthesia Research Unit (OARU), SRI
  • Active staff, department of anesthesia, Sunnybrook Health Sciences Centre
  • Associate professor, department of anesthesia, University of Toronto
  • Assistant professor, clinical epidemiology, Institute of Health Policy Management and Evaluation, School of Graduate Studies, U of T
  • Affiliate associate professor, pharmacology and therapeutics, department of anesthesiology, University of British Columbia

Invited Lectures and Visiting Professorships:

2014
  • Development of the Labor Pain Questionnaire. Anesthesia Grand Rounds. Sunnybrook Health Sciences Centre, Toronto, Canada. February 2014.

2013

  • Proposing Formal Clinical Diagnostic Criteria for Post-Epidural PDPH, Multicenter Canadian PDPH Trial. Richard Knill Competition, Canadian Anesthesiologists’ Society. Southlake Regional Hospital, Calgary, Canada. June 2013.
  • Postdural Puncture Headache in the Age of EBM. Anesthesia Grand Rounds. Southlake Regional Hospital, Newmarket, Canada. October 2013
  • Development of the Labor Pain Questionnaire. Obstetrics Grand Rounds, Sunnybrook Health Sciences Centre, Toronto, Canada. Nov. 1, 2013.

2012

  • Evidence Based Clinical Practice in OB Anesthesia: Using the Evidence Cycle for Articles Related to Therapy. Breakfast With the Experts Session, Society for Obstetrical Anesthesia and Perinatology Meeting, Monterey, U.S. May 2012.
  • The Complex Parturient. Canadian Anesthesiologists’ Society Annual Meeting, Quebec City, Canada. June 2012
  • Debate: Cesarean Section Should Be Managed With Low Dose CSE, Not High Dose Spinals With Vasopressors. Canadian Anesthesiologists’ Society Annual Meeting, Quebec City, Canada. June 2012
  • Labour Analgesia: State of the Art or State of the Evidence? Obstetric Anesthesia Meeting Day, Toronto Anesthetic Practice Meeting, Toronto, Canada. November 2012

2011

  • Evidenced Based Medicine/Epidural Morphine for Prevention of PDPH: Al-Metwalli article. Mixed anesthesia residents journal club, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada. Feb 23, 2011.
  • Current Concepts Regarding Post-Dural Puncture Headache. 52nd Annual McGill Anesthesia Update, McGill University, Montreal, Canada. May 22, 2011.
  • PDPH Update: Understanding and Treating it. Rural Emergency Continuum of Care Conference, Kelowna, Canada. June 15–18, 2011.
  • Issues and Barriers to Maternity Anesthesia Care in Ontario Hospitals With Fewer than 2,000 Deliveries per Annum (keynote speaker). Rural Emergency Continuum of Care Conference, Kelowna, Canada. June 15–18, 2011.
  • Should Labor Epidurals Be Considered a Negative Health Outcome? Rural Emergency Continuum of Care Conference, Kelowna, Canada. June 15–18, 2011.
  • Using the Evidence Cycle in Clinical Decision-Making. Canadian Anesthesiologists’ Society Annual Meeting, Toronto, Canada. June 25, 2011.
  • Reducing Maternal Risk Symposium (session chair). Canadian Anesthesiologists’ Society Annual Meeting. June 25, 2011.
  • Understanding and Designing a Simple RCT. Research Methods Symposium, Canadian Anesthesiologist’s Society Meeting, Toronto, Canada. June 2011.
  • Should Women Be Allowed To Eat During Labor? (session chair) Canadian Anesthesiologists’ Society Annual Meeting, Toronto, Canada. June 2011.
  • Evidence Based Approach to PDPH. Obstetric Anesthesia Meeting Day, Toronto Anesthetic Practice Meeting, Toronto, Canada. November 2011.
  • Patient Controlled Epidural Analgesia. Obstetric Anesthesia Meeting Day, Toronto Anesthetic Practice Meeting, Toronto, Canada. November 2011.

2010

  • Through the Looking Glass: Examining Evidence in Obstetrical Anesthesia. Canadian Anesthesiologists’ Society Annual Meeting, Montreal, Canada. June 2010.
  • PDPH Update. Ontario Medical Association Meeting, Toronto, Canada. October 2010.
  • Nuts and Bolts of Operationalizing Your Trial. Introduction to Randomized Controlled Trials, department of clinical epidemiology, Institute of Health Policy Management and Evaluation Program, University of Toronto, Toronto, Canada. November 2010.
  • The Case of a Woman With Headache and Diplopia After an Epidural. 5th Annual Obstetric Anesthesia Day, Toronto, Canada. Nov 26, 2010.
  • Should Epidurals Be Considered a Negative Outcome? Pregnancy and Birth Conference, Toronto, Canada. December 2010.

Committees:

  • National Maternity Guidelines Writing Committee (Family Centered Maternity Care), Canada
  • University of Toronto, Continuing Medical Education Committee, Department of Anesthesia

Honours, Awards and Major Grants:

  • 1999–2000, Physicians' Services Inc. Foundation
  • 2007–2008, RA Gordon Patient Safety Award, Canadian Anesthesiologists' Society
  • 2007–2008, Physicians' Services Inc. Foundation
  • 2008, RA Gordon Clinical research Award, Canadian Anesthesiologists' Society
  • 2009–2011, Merit Award, University of Toronto
  • 2014–2015, Academic Health Science Centre Alternate Funding Plan (AFP), Ontario Medical Association and the Ministry of Health and Long-Term Care

Research Profile

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Administrative Assistant: Doris Cheung
Phone: 416-480-6100, ext. 87757
Fax: 416-480-5614
Email: doris.cheung@sunnybrook.ca

Education:

  • MD, 1988, Harvard University, U.S.
  • M.Sc., 1994, health research methodology, McMaster University, Canada
  • M.Sc., 2013, evidence-based health care programme, Oxford University, UK
  • PhD candidate, evidence-based health care programme, Oxford University, UK

Appointments and Affiliations:

  • Associate scientist, Evaluative Clinical Sciences, Women & Babies Research Program, Sunnybrook Research Institute (SRI)
  • Director, Obstetrical Anesthesia Research Unit (OARU), SRI
  • Active staff, department of anesthesia, Sunnybrook Health Sciences Centre
  • Associate professor, department of anesthesia, University of Toronto
  • Assistant professor, clinical epidemiology, Institute of Health Policy Management and Evaluation, School of Graduate Studies, U of T
  • Affiliate associate professor, pharmacology and therapeutics, department of anesthesiology, University of British Columbia
  • Vice-chair, obstetrical anesthesia section, Canadian Anesthesiologists’ Society
  • Provincial Council for Child Health Ontario, Provincial Maternal Newborn Advisory Council

Research Foci:

  • Diagnosis, prevention and treatment of postdural puncture headache
  • Knowledge transfer and teaching evidence-based clinical practice
  • Development of new health measurement tools for use in obstetric anesthesia
  • Improving the quality of labour pain and post-caesarean pain relief

Research Summary:

  • Health measurement: development of a multidimensional psychometric instrument to measure women’s experiences of labour and delivery pain
  • Multicentre randomized controlled trial examining the use of small-gauge epidural needles and catheters to reduce the incidence and severity of postdural puncture headache
  • Health services research: women's access to obstetrical anesthesia services; knowledge translation
  • Post-caesarean analgesia: methods of measurement, treatment and prevention
  • Health research methodology
  • Evidence-based clinical practice in obstetrical anesthesia and knowledge transfer: development of a virtual hospital network for maternity anesthesia care in Ontario
  • Health measurement: development of a multi-attribute index to measure the quality of neuraxial analgesia for labour
  • Systematic reviews: labour pain and post-caesarean pain relief

Selected Publications:

See current publications list at PubMed.

  1. Angle P, Silva M, Halpern S, Kiss A. The validity of endpoint measurement. In: Ginosar Y, Halpern S, Reynolds F, Weiner CP, editors. Anesthesia and the fetus. Wiley-Blackwell; 2013. p. 75–88.
  2. Angle P, Landy CK, Charles C, Yee J, Watson J, Kung R, Kronberg J, Halpern S, Lam D, Lie LM, Streiner D. Phase 1 development of an index to measure the quality of neuraxial labour analgesia: exploring the perspectives of childbearing women. Can J Anesth., 2010 May;57(5):468–78.
  3. Angle P, Kurtz PA, Landy C, Murthy Y, Cino P. Key issues and barriers to obstetrical anesthesia care in Ontario community hospitals, with fewer than 2000 deliveries annually. Can J Anaesth. 2009 Sep;56(9):667–77.
  4. Morely-Forster P, Singh S, Angle P, Littleford J, Currin M, Halpern SH. The effect of epidural needle type on postdural puncture headache: a randomized trial. Can J Anaesth. 2006 Jun;53(6):572–8.
  5. Angle P, Hussain K, Morgan A, Halpern S, Van der Vyver M, Yee J et al. High quality labor analgesia using small gauge epidural needles and catheters. Can J Anaesth. 2006 Mar;53(3):263–7.

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