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Sunnybrook Research Institute

Bhushan Kapur, D.Phil., FRSC, FACB, FCACB

Associate scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room B2 04
Toronto, ON
M4N 3M5

Phone: 416-582-8611

Education

  • B.Sc. (Hons), 1959, Bombay University, India
  • D.Phil., 1967, organic chemistry, University of Basel, Switzerland
  • FRSC, 1980, Fellow, Royal Society of Chemistry, U.K.
  • FACB, 1984, Fellow, National Academy of Clinical Biochemistry, U.S.
  • FCACB, 1988, Fellow, Canadian Academy of Clinical Biochemistry

Appointments and Affiliations:

  • Associate scientist, Biological SciencesWomen & Babies Research Program, Sunnybrook Research Institute
  • Associate professor, department of laboratory medicine and pathobiology, faculty of medicine, University of Toronto
  • Consultant and scientific affiliate staff, department of clinical pathology, Sunnybrook Health Science Centre
  • Consultant toxicologist, division of clinical pharmacology and toxicology, Hospital for Sick Children
  • Specialist consultant in laboratory medicine and toxicology, addiction clinical consultation service, Centre for Addiction and Mental Health

Research Foci:

  • Biochemical changes in individuals who use or abuse alcohol 
  • Pharmacokinetics
  • Role of folic acid in pregnancy and alcohol-abusing patient 
  • Role of the toxicology laboratory in the management of the drug-abusing patient

Research Summary:

Dr. Kapur's research activities are focused on the following areas:

  1. Biochemical changes and mechanism of tissue injury in the alcohol-abusing patient.

    He has recently shown, for the first time, that formic acid from endogenously produced methanol, may be the cytotoxin responsible for tissue damage, including that which occurs in fetal alcohol syndrome. This work was supported by grants from the Canadian Institutes of Health Research and the Canadian Foundation on Fetal Alcohol Research. Current studies are focused on elucidating the mechanism of injury and possible ways to mitigate it.

  2. Role of folic acid in pregnancy and alcohol-abusing patient.
  3. Methadone as the treatment drug in the opiate-dependent patient.
  4. Role of the toxicology laboratory in management of the drug-abusing patient.

Selected Publications:

See current publications list at PubMed.

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