Scientist profiles M-R
Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room H1 71
Administrative Assistant: Antonella Iannaccio-Pesce
- MD, 1998, Federal University of Pernambuco, Brazil
- Residency, 2001, general surgery, Getúlio Vargas Hospital, Brazil
- Fellowship, 2006, trauma and general surgery research, Sunnybrook, U of T, Canada
- Fellowship, 2008, adult critical care medicine, Sunnybrook, U of T, Canada
- Fellowship, 2010, transfusion medicine, Sunnybrook, U of T, Canada
- Fellowship, 2011, critical care medicine, rapid response team, Sunnybrook, U of T, Canada
- M.Sc., 2012, clinical epidemiology, U of T, Canada
Appointments and Affiliations:
- Associate scientist, Evaluative Clinical Sciences, Trauma Emergency & Critical Care Research Program, Sunnybrook Research Institute
- Staff physician, department of surgery, Sunnybrook Health Sciences Centre
- Assistant professor of surgery, University of Toronto
- Resuscitation and coagulopathy in critically injured patients
- Quality improvement in trauma care
The focus of Dr. Nascimento's research is in clinical transfusion medicine, hemostasis and quality of care of bleeding patients during the initial resuscitation phase.
He is a member of Sunnybrook's Code Omega (life-threatening bleeding code) Committee and Transfusion Medicine Committee. He is also a member of the Canadian National Committee for Blood Shortage. In addition, Dr. Nascimento is part of the Sunnybrook's Trauma Research Group, which recently completed its first randomized controlled trial on massively bleeding trauma patients comparing a one red blood cell to one plasma to one platelet (formula-driven) transfusion strategy against a standard laboratory-guided transfusion strategy.
Dr. Nascimento is also co-investigator of the Pragmatic, Randomized, Optimal Platelet and Plasma Ratios (PROPPR) This Phase 3 multicentre, prospective, randomized controlled trial at level one adult trauma centers in North America, compares different ratios of blood products given to trauma patients who are predicted to require massive transfusions (greater than 10 units of packed red blood cells within the first 24 hours).
He is also the recipient of the 2010–2011 AABB National Blood Foundation grant to conduct research on early coagulopathy in trauma.
- Nascimento B, Callum J, Tien H, Rubenfeld G, Pinto R, Lin Y, Rizoli S. Effect of a fixed-ratio (1:1:1) transfusion protocol versus laboratory-results-guided transfusion in patients with severe trauma: a randomized feasibility trial. CMAJ. 2013 Sept. 3;185(12):E583–9.
- Nascimento B, Rizoli S, Rubenfeld G, Lin Y, Callum J, Tien HC. Design and preliminary results of a pilot randomized controlled trial on a 1:1:1 transfusion strategy: the trauma formula-driven versus laboratory-guided study. J Trauma. 2011 Nov;71(5 Suppl 1): S418–26.
- Nascimento B, Rizoli S, Rubenfeld G, Fukushima R, Ahmed N, Nathens A, Lin Y, Callum J. Cryoprecipitate transfusion: assessing appropriateness and dosing in trauma. Transfus Med. 2011 Dec;21(6):394–401.
- Nascimento B, Al Mahoos M, Callum J, Capone A, Pacher J, Tien H, Rizoli S. Vitamin K-dependent coagulation factor deficiency in trauma: a comparative analysis between international normalized ratio and thromboelastography. Transfusion. 2012 Jan;52(1):7–13.
- Nascimento B, Callum J, Rubenfeld G, Neto JB, Lin Y, Rizoli S.Clinical review: Fresh frozen plasma in massive bleedings¬-more questions than answers. Crit Care. 2010;14(1):202.
Related News and Stories:
- From fainting to familiarity: Undergraduate student overcomes initial fear of trauma for summer placement (Aug. 15, 2016)
- Moulding Medical Minds (Globe and Mail, May 23, 2013)
- Questions and Answers (IMS Magazine, November 2012)
- Changing the Face of Trauma Management (IMS Magazine, Winter 2011)