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Scientist profiles G-L

Sunnybrook Research Institute

Kullervo Hynynen M.Sc., PhD

Senior scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room S6 65B
Toronto, ON
M4N 3M5


Phone: 416-480-5717
Fax: 416-480-5714

Administrative Assistant: Marcelline Ramcharan
Phone: 416-480-6100, ext. 5765
Email: marcelline.ramcharan@sri.utoronto.ca

Education:

  • B.Sc., 1976, Physics, University of Kuopio, Finland
  • M.Sc., 1977, Physics, University of Kuopio, Finland
  • PhD, 1982, Biomedical Physics and Biomedical Engineering, University of Aberdeen, UK

Appointments and Affiliations:

  • Senior scientist, Physical Sciences (director), Odette Cancer Research Program, Sunnybrook Research Institute
  • Professor, department of medical biophysics, University of Toronto
  • Canada Research Chair in Imaging Systems and Image-Guided Therapy, Tier 1

Research Foci:

  • Focused ultrasound for noninvasive surgery
  • Vascular surgery
  • Targeted drug delivery and gene therapy
  • Ultrasound imaging and monitoring
  • MRI thermometry

Research Summary:

Dr. Hynynen's research has focused on studying the effects of ultrasound beams on tissue and their utilization in therapy. He is investigating the use of focused ultrasound for noninvasive surgery, vascular surgery, targeted drug delivery and gene therapy. He has developed theoretical models to help understand treatment parameters and to allow optimization of treatment devices. He has conducted in vivo experiments to investigate the various biological end points that can be induced by controlling the sonication parameters.

His research on ultrasound transducers has been used to design and develop new phased array applicators and better ways to deliver therapy. He is also looking at the use of magnetic resonance imaging to detect and quantify noninvasive ultrasound exposure in vivo. He has developed several systems that are being tested clinically. Dr. Hynynen is currently exploring new ways to utilize ultrasound for imaging with the aim of using the methods for controlling delivery of therapy and aid in tumour diagnosis.

Selected Publications:

See current publications list at PubMed.

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