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Job postings: Sunnybrook Research Institute

Ph.D. Student - 3D Bioprinting and Tissue Regeneration 

Posted: 3/1/2019 7:45:42 AM

Ph.D. Student

3D Bioprinting and Tissue Regeneration

The Sunnybrook Research Institute, fully affiliated with the University of Toronto, is seeking a highly motivated and enthusiastic candidate for a Ph.D. opportunity under the supervision of Dr. Marc Jeschke. The prospective Ph.D. candidate will join the stem cell and skin regeneration team in the lab. Our group utilizes in vitro and in vivo approaches to shed light on the process of healing after a burn injury. Different sources of stem cells are employed in combination with novel biocompatible materials to create skin substitutes that can be used on patients with burns. The research aim of this position is to use advanced biomanufacturing technologies including 3D bioprinting to develop physiological functioning skin tissues or skin substitutes containing stem cells as innovative cell-based therapeutic solutions to improve wound healing and promote skin regeneration after thermal injuries. The candidate is, therefore, expected to work on the multidisciplinary interface of additive manufacturing, material science, microengineering, stem cell biology, immunology, biology of wound healing and scarring. This will develop a wide skill set including the engineering of 3D bioprinter and microfluidic devices, 3D bioprinting of tissues, bioink development, material characterization, stem cell research, and the capability of writing highly visible scientific publications in the field of regenerative medicine and tissue engineering.

Dr. Marc Jeschke is a Senior Scientist, division of Biological Sciences at Sunnybrook Research Institute, and the director of the Ross Tilley Burn Centre (RTBC). The RTBC is the largest burn centre in Canada and treats patients with minor and major burn injuries. Dr. Marc Jeschke has appointments with the University of Toronto Department of Surgery and Divisions of Plastic and General Surgery, Department of Immunology and Institute of Medical Sciences. The University of Toronto ranks #1 in Canada and #20 globally in the most recent U.S. News and World Report’s rankings of the world’s best universities. The admission of the prospective candidate must be accepted by the Institute of Medical Sciences (IMS). Admission requirements and other information about applying can be found here on IMS website: https://ims.utoronto.ca/apply-here/admissions/


Qualifications:

  • Completion of a Master’s degree or equivalent in Biomedical Sciences, Biomedical Engineering, Materials Science, or an equivalent discipline. Candidates with Bachelor’s degree in the relevant discipline with extensive trainings or research experience in the related field are also encouraged to apply.
  • Strong understanding and interest in molecular biology, stem cell therapy, additive manufacturing and tissue engineering.
  • Strong desire of learning and employing in vitro and in vivo approaches to achieve the research goals. Previous in vivo animal study experience would be a big plus.
  • Strong interest with some practical experience in 3D (bio)printing, material synthesis/characterization, and/or development of microfluidic devices. Hands-on experience in 3D printer and/or bioink development would be considered as a strong asset.
  • Knowledge of 3D design and some experience utilizing mainstream 3D modeling software such as Solidworks, Fusion 360, Geomagic Design. Some programming knowledge in languages like Python etc. would be preferred.
  • Fundamental experimental skills in molecular and cell biology such as cell culture techniques
  • Excellent analytical skills with critical thinking and an innate ability for solution-oriented problem solving.
  • Excellent social and communication skills, in academic as well as non-academic contexts.
  • Strong willingness to effectively work independently and as part of a team in which fundamental and applied research cross-fertilize.
  • Possess a creative and critical attitude, combined with perseverance and being flexible and stress-resistant.
  • Fluent in English language skills, both in speaking and writing.

Interested candidates are invited to submit your pre-application package consisting of the followings to Andrea-Kaye Datu (Email: andreak.datu@sunnybrook.ca) with “Ph.D. Opportunity - 3D Bioprinting and Tissue Regeneration” the subject line. We thank all applicants for their interest but only candidates selected for an interview will be contacted.

  • a cover letter (maximum 1 page), emphasizing brief description of research experience, specific interests, qualifications and motivations to apply for this opportunity.
  • a full Curriculum Vitae.
  • a copy of official transcript.
  • a short descriptive document (maximum 1 page excluding references) to outline your proposed thesis research project.

Sunnybrook Research Institute is committed to providing accessible employment practices that are in compliance with the Accessibility for Ontarians with Disabilities Act (AODA). If you require accommodation for disability during any stage of the recruitment process, please indicate this in your cover letter.

Sunnybrook Research Institute is strongly committed to inclusion and diversity within its community and welcomes all applicants including but not limited to: visible minorities, all religions and ethnicities, persons with disabilities, LGBTQ persons, and all others who may contribute to the further diversification of ideas.