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Scientist profiles M-R

SRI Profiles

Laurent Milot, M.Sc., MD

Affiliate scientist

Sunnybrook Health Sciences Centre
2075 Bayview Avenue, Room AG 279
Toronto, ON
M4N 3M5

Administrative Assistant: Ellen Tyson
Phone: 416-480-6100, ext. 4339
Email: ellen.tyson@sunnybrook.ca

Phone: 416-480-6100, ext. 7418
Fax: 416-480-5855

Education:

  • Medical undergraduate studies, 2001, Faculty of Medicine, University Paris Descartes, France
  • M.Sc., 2005, medical engineering, Université Claude Bernard Lyon I, France
  • MD, 2006, Université Claude Bernard Lyon I, France
  • Specialty, 2006, medical imaging, Université Claude Bernard Lyon I, France

Appointments and Affiliations:

  • Affiliate scientist, Physical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute
  • Associate professor, department of medical imaging, University of Toronto
  • Associate member, Institute of Medical Science, U of T
  • Associate vice-chair of research, growth, development and neoplasia, department of medical imaging, U of T
  • Staff radiologist, Sunnybrook Health Sciences Centre

Research Foci:

  • MRI biomarkers of colorectal cancer liver metastases
  • Radiogenomics
  • Image-guided therapy
  • Co-registration of imaging modalities
  • Body MRI
  • Contrast-enhanced ultrasound
  • Elastography

Research Summary:

Dr. Milot’s research revolves around the determination of prognoses using novel MRI biomarkers of people with colorectal liver metastases that are treated with advanced surgery.

He is interested in image-guided therapy, with a focus on the development and evaluation of new approaches in the treatment of cancers. He has a special interest in hepatobiliary imaging, as well as intestinal imaging.

He is using new techniques of co-registration of imaging modalities for diagnostic, functional and therapeutic purposes. He has a special interest in imaging that quantifies the elastic properties of tissues for diagnostic purposes and for evaluation of response to therapy.

Selected Publications:

See current publications list at PubMed.

  1. Cheung HMC, Karanicolas PJ, Hsieh E, Coburn N, Maraj T, Kim JK, Elhakim H, Haider MA, Law C, Milot L. Late gadolinium enhancement of colorectal liver metastases post-chemotherapy is associated with tumour fibrosis and overall survival post-hepatectomy. Eur Radiol. 2018 Aug;28(8):3505–12. doi: 10.1007/s00330-018-5331-4. Epub 2018 Feb 23.
  2. Milot L, Ma K, Efford E, Sela G, Coburn N, Haider M, Piron C, Plewes D, Law C. Evaluation of a multimodality MR/US coregistration system for investigation of hepatic metastases from colorectal cancer. J Vasc Interv Radiol. 2013 Mar;24(3):357–62. doi: 10.1016/j.jvir.2012.11.018. Epub 2013 Jan 24.
  3. Al-Sukhni E, Milot L, Fruitman M, Beyene J, Victor JC, Schmocker S, Brown G, McLeod R, Kennedy E. Diagnostic accuracy of MRI for assessment of T category, lymph node metastases and circumferential resection margin involvement in patients with rectal cancer: a systematic review and meta-analysis. Ann Surg Oncol. 2012 Jul;19(7):2212–23. doi: 10.1245/s10434-011-2210-5. Epub 2012 Jan 20.
  4. Milot L, Guindi M, Gallinger S, Moulton CA, Brock K, Dawson L, Haider MA. MRI correlates of intratumoral tissue types within colorectal liver metastases: a high-spatial-resolution fresh ex vivo radiologic-pathologic correlation study. Radiology. 2010 Mar;254(3):747–54.
  5. Baboi L, Pilleul F, Milot L, Lartizien C, Poncet G, Roche C, Scoazec JY, Beuf O. Magnetic resonance imaging follow-up of liver growth of neuroendocrine tumors in an experimental mouse model. Magn Reson Imaging. 2010 Feb;28(2):264–72.

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