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Evaluative Clinical Sciences

SRI platforms

Eileen Rakovitch, MD, FRCP(C), M.Sc.

Scientist

Sunnybrook Health Sciences Centre
Odette Cancer Centre
Department of Radiation Oncology, T wing
2075 Bayview Ave.
Toronto, ON
M4N 3M5

Phone: 416-480-4834
Fax: 416-480-6002

Administrative Assistant: Fatima Malik
Phone: 416-480-4834
Email: fatima.malik@sunnybrook.ca

Education:

  • MD, 1989, Faculty of Medicine, University of Toronto, Canada
  • FRCP(C), 1995, Department of Radiation Oncology, University of Toronto, Canada
  • M.Sc., 2004, Clinical Epidemiology, Health Policy Management and Evaluation, University of Toronto, Canada

Appointments and Affiliations:

Research Foci:

  • Health services
  • Population-based studies
  • Breast cancer

Research Summary:

Ductal carcinoma in situ (DCIS) represents 20 – 40% of newly diagnosed breast cancers. DCIS itself is not life threatening, however some women with DCIS will develop life-threatening invasive breast cancer. At the present time, we are unable to identify which women will progress to invasive cancer due to small sample size in many studies and variable pathologic evaluation of specimens. Therefore, all women with DCIS undergo surgical treatment often followed by radiation.

This study will establish the largest cohort of DCIS in the world and will be the only population-based study of DCIS with full description of treatment and outcomes and will include complete pathology review. The results of this study will help identify women with DCIS at greatest risk of recurrence, and will facilitate targeting of treatments to those at risk while avoiding unnecessary morbidity for the majority of women with DCIS who will never die of breast cancer.

Selected Publications:

See current publications list at PubMed.

    1. Rakovitch E, Pignol J-P, Chartier C, Ezer M, Verma S, Dranitsaris G, Clemons M. Complementary and Alternative Medicine Use Is Associated with An Increased Perception of Breast Cancer Risk and Death. Breast Cancer Research and Treatment 90(2):139-148, 2005.
    2. Rakovitch E, Mihai A, Pignol J-P, Hanna W, Kwinter J, Chartier C, Ackerman I, Kim J, Pritchard K, Paszat L. Is Expert Pathology Assessment Necessary for the Management of Ductal Carcinoma In Situ? Breast Cancer Research and Treatment, 87(3):265-272, 2004
    3. Rakovitch E, Tsao M, Ung Y, Pignol J-P, Cheung P, Chow E. A Comparison of the Efficacy and Acute Toxicity of Weekly Versus Daily Chemoradiation For Non-Small Cell Lung Cancer: A Meta-Analysis. International Journal of Radiation Oncology, Biology and Physics, 58(1):196-203, 2004.
    4. Rakovitch E, Franssen E, Kim J, Ackerman I, Pignol J-P, Paszat L, Pritchard K, Ho C, Redelmeier D. A Comparison of Risk Perception and Psychological Morbidity In Women With Ductal Carcinoma In Situ And Early Invasive Breast Cancer. Breast Cancer Research and Treatment 77(3):285-293, 2003.
    5. Rakovitch E, Wright B, Shumak R, Catzavelos C, Holloway C, Kim J. Ductal Carcinoma In Situ. Current Problems in Cancer 24(3):93-176, 2000.

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