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Department of Surgery
Hospital  >  Departments  >  Surgery  >  Orthopaedic Surgery

Department of Surgery

Orthopaedic Surgery

Dr. Albert J.M. Yee, MD, M.Sc.,FRCSC, DABOS

Associate scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room MG 371B
Toronto, ON
M4N 3M5

Phone: 416-480-6815
Fax: 416-480-5886

Clinical Assistant: Ala Bankowska

Dr. Albert Yee is Program Chief of the Holland Bone and Joint Research Program and Division Head (Marvin Tile Chair in Orthopaedic Surgery) for Sunnybrook.

Dr. Yee began his career with Sunnybrook in 2001. He is a professor at the University of Toronto, faculty of medicine, department of surgery, where he also serves as vice chair of research, division of orthopaedics, and co-director of the department of surgery spine program. He is an associate scientist at Sunnybrook Research Institute and is a full member of the Institute of Medical Science, faculty of medicine, with a cross appointment at the Institute of Biomaterials and Biomedical Engineering, faculty of applied science and engineering, University of Toronto. A graduate of the university, he holds specialty certification in orthopaedic surgery from the Royal College of Physicians and Surgeons of Canada and he has obtained specialty certification in orthopaedics and spine from the American Board of Orthopaedic Surgery.


  • MD, 1992, faculty of medicine, University of Toronto, Canada
  • M.Sc., 1996, Institute of Medical Science, surgeon-scientist program, U of T
  • FRCS(C), fellow of the Royal College of Physicians and Surgeons Canada, orthopaedic surgery
  • 2003–present, diplomate of the American Board of Orthopaedic Surgery
  • 1999–2001, clinical and research fellowship, R. Samuel McLaughlin Foundation fellowship in spine surgery, Case Western Reserve University, Cleveland, U.S.

Appointments and Affiliations:

  • Associate scientist, Physical Sciences, Holland Bone and Joint Research Program, Sunnybrook Research Institute
  • Consultant in surgical oncology, bone metastases clinic, Odette Cancer Centre, Sunnybrook Health Sciences Centre
  • Professor, department of surgery, division of orthopaedic surgery, U of T
  • Co-director, department of surgery spine program, U of T
  • Vice-Chair research, division of orthopaedics, U of T
  • Full member, Institute of Medical Sciences, faculty of medicine, U of T
  • Cross-appointed, Institute of Biomaterials and Biomedical Engineering and Toronto Musculoskeletal Centre, U of T

Research Focus:

  • Preclinical models of spinal surgery
  • Vertebral metastases
  • Intervertebral disc cell metabolism

Research Summary:

The ultimate goal of Dr. Yee's spine research program is to bring forth novel therapies from the bench-top to the clinical setting. As such, the development and use of preclinical models in surgery are important in evaluating potential new therapies for the treatment of spinal disorders. The fundamental aspects of understanding cell-matrix interactions in intervertebral disc and cancer biology will further the development and preclinical evaluation of minimally invasive local strategies targeted against degenerative and metastatic conditions of the spine.

Selected Publications:

See current publications list at PubMed.

  1. Malempati H, Wadey V, Paquette S, Kreder H, Massicotte E, Rampersaud R, Fisher C, Dvorak M, Fehlings M, Backstein D, Yee A. Spinal surgery fellowship education in Canada: evaluation of trainee and supervisor perspectives on cognitive and procedural competencies. Spine. 2013;38(1):83–91.
  2. Du WW, Yang W, Yee AJ. Roles of versican in cancer biology-tumorigenesis, progress and metastasis. Histol and Histopathol. 2013;28(6):701–13.
  3. Du WW, Yang BB, Seth A, Yee AJ. Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy. PLoS ONE. 2011;6(11):e26396.
  4. Bederman SS, Murnaghan O, Lansang E, Malempati H, Johnston E, Wilkinson M, Bronstein Y, Finkelstein JA, Yee AJ. In-hospital mortality and surgical utilization in severely polytraumatized patients with and without spinal injury. J Trauma. 2011:71(4): pp E71–8.
  5. Akens MA, Hardisty M, Whyne C, Burch S, Wilson BC, Schwock J, Yee AJ. Defining the therapeutic window of vertebral photodynamic therapy in a murine pre-clinical model of breast cancer metastasis using the photosensitizer BPD-MA (Verteporfin). Breast Cancer Res Treat. 2010 Jan;119(2):325–33.

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