Cancer trials: Search results
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A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF INAVOLISIB IN COMBINATION WITH PHESGO VERSUS PLACEBO IN COMBINATION WITH PHESGO AS MAINTENANCE THERAPY AFTER FIRST LINE INDUCTION THERAPY IN PARTICIPANTS WITH PIK3CA MUTATED HER2 POSITIVE LOCALLY ADVANCED OR METASTATIC BREAST CANCER
Trial short name: INAVO-122
Cancer type: Breast
Cancer location: Breast
Disease stage: Advanced Cancer
Trial phase: Phase 3
A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF INAVOLISIB IN COMBINATION WITH PHESGO VERSUS PLACEBO IN COMBINATION WITH PHESGO AS MAINTENANCE THERAPY AFTER FIRST LINE INDUCTION THERAPY IN PARTICIPANTS WITH PIK3CA MUTATED HER2 POSITIVE LOCALLY ADVANCED OR METASTATIC BREAST CANCER
Trial short name: INAVO-122
Cancer type: Breast
Cancer location: Breast
Disease stage: Advanced Cancer
Trial phase: Phase 3
A Liquid-Biopsy Informed Platform Trial To Evaluate Treatment In CDK4/6-Inhibitor Resistant ER+/HER2- Metastatic Breast Cancer
Trial short name: IND.241
Cancer type: Breast
Cancer location: Breast
Disease stage: Advanced Cancer
Trial phase: Phase 2
MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer: A Multi-centre Prospective Cohort Study
Trial short name: INSIGHT
Cancer type: Breast
Cancer location: Breast
Disease stage: Early Cancer
Trial phase: Other
Phase Ib/II Trial of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-365)
Trial short name: KN365 Prostate
Cancer type: Genitourinary
Cancer location: Prostate
Disease stage: Early Cancer
Trial phase: Phase 1, Phase 2
A Phase 3 Study of Fixed Dose Combinations of Fianlimab and Cemiplimab Versus Relatlimab and Nivolumab in Participants with Unresectable or Metastatic Melanoma
Trial short name: LAG3 COMBO
Cancer type: Melanoma
Cancer location: Melanoma
Disease stage: Advanced Cancer
Trial phase: Phase 3
A phase 3 trial of fianlimab (REGN3767, Anti-Lag3) + cemiplimab versus pembrolizumab in patients with previously untreated unresectable locally advanced or metastatic melanoma
Trial short name: LAG3 REGN MEL
Cancer type: Melanoma
Cancer location: Melanoma
Disease stage: Early Cancer
Trial phase: Phase 3
NRG-BR007: A PHASE III CLINICAL TRIAL EVALUATING DE-ESCALATION OF BREAST RADIATION FOR CONSERVATIVE TREATMENT OF STAGE I, HORMONE SENSITIVE, HER2-NEGATIVE, ONCOTYPE RECURRENCE SCORE ≤ 18 BREAST CANCER
Trial short name: MAC.28 (DEBRA)
Cancer type: Breast
Cancer location: Breast
Disease stage: Early Cancer
Trial phase: Phase 3
OptimICE-pCR: De-Escalation of Therapy in Early Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy
Trial short name: MAC.29 OPTIMICE
Cancer type: Breast
Cancer location: Breast
Disease stage: Early Cancer
Trial phase: Phase 3
Management of National MDS Clinical Database and Local Tissue Bank
Trial short name: MDS Database
Cancer type: Blood Related
Cancer location: Myelodysplastic Syndromes
Disease stage: Other
Trial phase: Other
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II)
Trial short name: ME.15
Cancer type: Melanoma
Cancer location: Melanoma
Disease stage: Early Cancer
Trial phase: Phase 3
A randomized phase II trial of adjuvant melanoma with or without cabozantinib in patients with resected mucosal melanoma.
Trial short name: MEC.6
Cancer type: Melanoma
Cancer location: Melanoma
Disease stage: Early Cancer
Trial phase: Phase 2
A PHASE 3, RANDOMIZED, OPEN-LABEL STUDY OF PF-06821497 (MEVROMETOSTAT) IN COMBINATION WITH ENZALUTAMIDE COMPARED WITH ENZALUTAMIDE OR DOCETAXEL IN PARTICIPANTS WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER PREVIOUSLY TREATED WITH ABIRATERONE ACETATE (MEVPRO-1)
Trial short name: MEVPRO-1
Cancer type: Genitourinary
Cancer location: Prostate
Disease stage: Advanced Cancer
Trial phase: Phase 3
Molecular, Imaging, and Neurological assessment Database for CNS tumours
Trial short name: MIND-CNS
Cancer type: Central Nervous System
Cancer location: Central Nervous System
Disease stage: Early Cancer
Trial phase: Other
A Phase 3, Randomized, Double-blind, Multicenter Study of MK-1084 in Combination With Pembrolizumab Compared With Pembrolizumab Plus Placebo as Firstline Treatment of Participants With KRAS G12C-Mutant, Metastatic NSCLC With PD-L1 TPS ≥50%
Trial short name: MK-1084-004
Cancer type: Lung
Cancer location: Lung
Disease stage: Advanced Cancer
Trial phase: Phase 3
A Phase 3, Randomized, Double-blind, Multicenter Study of MK-1084 in Combination With Pembrolizumab Compared With Pembrolizumab Plus Placebo as Firstline Treatment of Participants With KRAS G12C-Mutant, Metastatic NSCLC With PD-L1 TPS ≥50%
Trial short name: MK-1084-004
Cancer type: Lung
Cancer location: Lung
Disease stage: Advanced Cancer
Trial phase: Phase 3
A Phase 3 Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) Previously Treated With Next-generation Hormonal Agent (NHA) and Taxane-based Chemotherapy
Trial short name: MK-5684-003
Cancer type: Genitourinary
Cancer location: Prostate
Disease stage: Early Cancer
Trial phase: Phase 3
The Multiple OutcoMe EvaluatioN of radiation Therapy Using the MR-linac Study
Trial short name: MOMENTUM
Cancer type: Central Nervous System
Cancer location: Other (Central Nervous System)
Disease stage: Other
Trial phase: Other
An Open-label Randomized Phase 3 Study of Tucatinib in Combination with Trastuzumab and mFOLFOX6 versus mFOLFOX6 given with or without either Cetuximab or Bevacizumab as First-line Treatment for Subjects with HER2+ Metastatic Colorectal Cancer
Trial short name: MOUNTAINEER-03
Cancer type: Gastrointestinal
Cancer location: Gastrointestinal
Disease stage: Early Cancer
Trial phase: Phase 3
National Clinical Melanoma Database
Trial short name: National Melanoma Database
Cancer type: Melanoma
Cancer location: Melanoma
Disease stage: Early and Advanced Cancer
Trial phase: Other
A randomized study of cessation of somatostatin analogues after Peptide Receptor Radionuclide Therapy in Mid, Hind-Gut and Pancreatic Neuroendocrine tumours
Trial short name: NE.2
Cancer type: Neuroendocrine
Cancer location: Neuroendocrine
Disease stage: Early Cancer
Trial phase: Phase 2
Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Trial short name: NRG-GY019
Cancer type: Gynecology
Cancer location: Gynecology
Disease stage: Early Cancer
Trial phase: Phase 3
OCELOT – Osimertinib then Chemotherapy in EGFR-mutated Lung cancer with Osimertinib Third-line rechallenge
Trial short name: OCELOT
Cancer type: Lung
Cancer location: Lung
Disease stage: Early Cancer
Trial phase: Phase 2
ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study
Trial short name: ONC201-108
Cancer type: Central Nervous System
Cancer location: Central Nervous System
Disease stage: Early Cancer
Trial phase: Phase 3
OURA Ring Wearable Testing in MDS Patients: a feasibility and discovery pilot study
Trial short name: OURA MDS
Cancer type: Blood Related
Cancer location: Myelodysplastic Syndromes
Disease stage: Early Cancer
Trial phase: Other
