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Scientist profiles M-R

Alan Moody, MBBS, FRCP, FRCR

Senior scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room AG 57
Toronto, ON
M4N 3M5

Phone: 416-480-6100, ext. 4341
Fax: 416-480-5855

Administrative Assistant: Ellen Tyson
Phone: 416-480-6100, ext. 4339
Email: ellen.tyson@sunnybrook.ca

Education:

  • BA (Hons), 1980, physiology, University of Oxford, UK
  • MBBS, 1983, St. Thomas’s Hospital, UK
  • FRCP, 1983, Royal College of Physicians, UK
  • FRCR, 1986, Royal College of Radiologists, UK

Appointments and Affiliations:

  • Senior scientist, Physical Sciences, Schulich Heart Research Program, Sunnybrook Research Institute
  • Staff physician, medical imaging, Sunnybrook Health Sciences Centre
  • Chair and professor, department of medical imaging, University of Toronto
  • Associate professor, Institute of Medical Science, School of Graduate Studies, University of Toronto
  • Associate professor, department of medical biophysics, University of Toronto

Research Foci:

  • Vascular imaging
  • Vascular biology
  • Atheroma
  • Perfusion
  • Thrombosis
  • Disease process

Research Summary:

Magnetic resonance imaging (MRI) has rapidly established itself as a major imaging technique for the visualization of vascular diseases. In particular, magnetic resonance direct thrombus imaging (MRDTI) provides a closer, more in-depth look into occluded arteries, providing information never seen before, and has the potential of changing the standard of imaging everywhere. This new MRI technique aims at early diagnosis and intervention to prevent strokes and heart attacks by detecting vulnerable plaques in arteries of patients who are asymptomatic.

Dr. Moody and his team are interested in developing and incorporating such imaging techniques in a comprehensive effort to identify and stabilize vulnerable plaques in one integrated procedure. Applications of MRDTI in the coronary, renal arteries and aorta are also underway.

The following areas are also under investigation using MRDTI:

  • ischemia;
  • treatment of occlusive vascular disease;
  • atherosclerotic plaque in the coronary and neurovascular circulations;
  • deep venous thromboses; and
  • diagnostic utility in endometriosis.

Selected Publications:

See current publications list at PubMed.

  1. Bitar R, Moody AR, Leung G, Kiss A, Gladstone D, Sahlas DJ, Maggisano R. In vivo identification of complicated upper thoracic aorta and arch vessel plaque by MR direct thrombus imaging in patients investigated for cerebrovascular disease. AJR Am J Roentgenol. 2006 Jul;187(1):228-34.
  2. Bitar R, Leung G, Perng R, Tadros S, Moody AR, Sarrazin J, McGregor C, Christakis M, Symons S, Nelson A, Roberts TP. MR pulse sequences: what every radiologist wants to know but is afraid to ask. Radiographics. 2006 Mar-Apr;26(2):513-37.
  3. Daniels LR, Gladman JR, Altaf N, Moody AR. Magnetic resonance direct thrombus imaging in moderate carotid artery stenosis. Stroke. 2006 Mar;37(3):767-8.
  4. Bitar R, Gladstone D, Sahlas D, Moody A. MR angiography of subclavian steal syndrome: pitfalls and solutions. AJR Am J Roentgenol. 2004 Dec;183(6):1840-1
  5. Fraser DG, Moody AR, Morgan PS, Martel A. Iliac compression syndrome and recanalization of femoropopliteal and iliac venous thrombosis: a prospective study with magnetic resonance venography. J Vasc Surg. 2004 Oct;40(4):612-9.

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