Research opportunity:

Have you had a stroke in the last 2-12 months and still have leg weakness after your stroke?

We are looking for people to participate in the FLOW Trial (Fluoxetine to Open the Critical Period Time Window to Improve Motor Recovery after Stroke).

This trial looks at the effects of low-dose Fluoxetine, a commonly used antidepressant, which may help leg recovery when paired with exercise following stroke. You will be randomized to receive either Fluoxetine or placebo.

Participants will:

  • Take the trial medication for 19-21 weeks
  • Receive 12-weeks of supervised exercise at Toronto Rehab – Rumsey Centre
  • Complete 3 additional study visits at Sunnybrook Health Sciences Centre

You may be eligible if you:

  • Are 25 years of age or older
  • Experiences a stroke in the last 2-12 months
  • Have significant leg weakness in at least one leg

Parking and/or travel expenses will be provided.

More information regarding the FLOW trial can be found here »

If you are interested in learning more, please call 416-480-6100 ext. 685406 or email Our research team will contact you to provide more details and determine eligibility for participation.

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