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COVID-19: Participate in research
Hospital  >  Patients & Visitors  >  COVID-19 (2019 novel coronavirus): information & resources  >  COVID-19 Information and Resources  >  COVID-19 Research  >  Participate in research  >  SAVE-ICU: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU

SAVE-ICU: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU

SAVE-ICU is a multi-centre, randomized clinical trial studying the effectiveness of inhaled volatile sedation versus intravenous sedation for COVID-19 patients that need to be placed on a ventilator.

The purpose of the study is to evaluate whether inhaled volatile sedation can be used effectively in ventilated COVID-19 patients, thereby easing pressure on IV sedation stocks. The study is also evaluating if patients recover faster with this form of sedation.

You may be eligible to participate if you:

  • Are 18 years of age or older
  • Mechanically ventilated with proven or suspected COVID-19 disease or suffering from hypoxic lung failure

Participants will:

  • Be randomized to one of the treatment groups, while hospitalized
  • Receive intravenous or inhaled sedation, administered according to standard sedation practice
  • Be followed-up with throughout their ICU stay and up to one year after

If you or a family member are admitted to Sunnybrook Hospital and interested in participating in this trial or want to learn more information, please talk to your doctor about the SAVE-ICU trial or email

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