SAVE-ICU: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU
SAVE-ICU is a multi-centre, randomized clinical trial studying the effectiveness of inhaled volatile sedation versus intravenous sedation for COVID-19 patients that need to be placed on a ventilator.
The purpose of the study is to evaluate whether inhaled volatile sedation can be used effectively in ventilated COVID-19 patients, thereby easing pressure on IV sedation stocks. The study is also evaluating if patients recover faster with this form of sedation.
You may be eligible to participate if you:
- Are 18 years of age or older
- Mechanically ventilated with proven or suspected COVID-19 disease or suffering from hypoxic lung failure
Participants will:
- Be randomized to one of the treatment groups, while hospitalized
- Receive intravenous or inhaled sedation, administered according to standard sedation practice
- Be followed-up with throughout their ICU stay and up to one year after
If you or a family member are admitted to Sunnybrook Hospital and interested in participating in this trial or want to learn more information, please talk to your doctor about the SAVE-ICU trial or email SAVE-ICU@sunnybrook.ca.