Scientist profiles G-L

Gariépy is a senior scientist in Physical Sciences at SRI. His lab is developing agents that target immune system responses by selectively dampening them, as in autoimmune disorders, or stimulating them, to fight cancer.

He recently published a study in JCI Insight that details a link between mutations in the p53 gene, which halts tumour growth and is the most frequently altered gene in cancer, and survival in people with cancer. It shows that more active mutations of p53 are associated with longer survival, suggesting a path by which the gene’s mutation status could help determine prognosis and guide treatment.