Evaluative Clinical Sciences

Administrative Assistant: Lisa Keable
Phone: 416-480-6838
Fax: 416-480-6840
Email: lisa.keable@sunnybrook.ca

Education:

• BA, 1982, computer science and mathematics, Western University, Canada
• MD, 1986, faculty of medicine, University of Toronto, Canada
• FRCSC, 1991, orthopaedic residency, Western University, Canada

Appointments and Affiliations:

• Associate professor of surgery, University of Toronto
• Susanne and William Holland Chair in Sports Medicine Research
• Associate scientist, Evaluative Clinical Sciences, Holland Bone and Joint Research Program, Sunnybrook Research Institute
• Staff surgeon, division of orthopaedic surgery, Sunnybrook
• Medical director and Orthopaedic Surgeon, National Basketball Association, Toronto Raptors.
  

Research Focus:

• Risk factors and osteoarthritis progression after anterior cruciate ligament injury

Research Summary:

Dr. Marks has a special interest in sports medicine, arthroscopy and reconstruction of the shoulder and knee. His research activities involve imaging, biomechanics, ultrastructural morphology, and clinical aspects of the cruciate and meniscofemoral ligaments.

He holds grants from the Canadian Institutes of Health Research and the Canadian Arthritis Network for research in predicting factors for developing arthritis in the knee. He is part of the multidisciplinary team studying cytokine and biomarker imaging and outcome measures in patients at risk for developing arthritis.

Dr. Marks is also part of the ProKnee study, which is a multi-institutional research group that spans three Canadian cities: Toronto, Calgary and Montreal. The ProKnee study, the first of its kind in Canada, examines the relationship between risk factors and the progression of osteoarthritis after anterior cruciate ligament injury. Several assessment criteria are used, all of which rely on the meticulous reporting of clinical data from Dr. Marks' practice. Particularly, mathematical and in vivo models of specific tissue deficits are constructed to approximate the lesions found in patients’ knees.

Selected Publications:

See current publications list at PubMed.

1. Brooks-Hill AL, Marks P. Hip flexion may prevent ACL injury: a biomechanical explanation. Clinical Journal of Sports Medicine. Pennsylvania: 2005.
2. Griffin LY, Albohm MJ, Arendt EA, Bahr R, Beynnon BD, DeMaio M, Dick RW, Engebresten L, Garrett WE Jr., Hannafin JA, Hewett TE, Juston LJ, Lloyd Ireland M, Johnson RJ, Lephart S, Mandelbaum BR, Mann B, Marks PH. Update of ACL injury prevention: theoretical and practical considerations a review of the Hunt Valley II meeting, February 2005. American Journal of Sports Medicine. Pennsylvania (U.S.): 2005. p. 53.
3. Pagura SMC, Thomas SG, Woodhouse LJ, Ezzat S, Marks P. Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men. Journal of Orthopaedic Research. Pennsylvania (U.S.): 2004: p. 9.
4. Marks PH, Droll KP, Cameron M. Does ACL reconstruction prevent articular degeneration? The ACL risk equation. In: Williams RJ, Johnson DP, editors. Controversies in knee surgery. New York (U.S.): Oxford University Press; 2004. p. 22.
5. Richards D, Yee G, Marks, PH. Basketball injuries. In: McGraw-Hill Professional, editor. Bull’s handbook of sports injuries. 2nd ed. New York (U.S.): Medical Publishing Division; 2004. p. 1.

Related News and Stories:

• Team effort: Orthopaedic surgeon works with researchers across the country to predict risk factors for a debilitating disease striking one in 10 Canadians (SRI Magazine, 2008)