Evaluative Clinical Sciences

High risk pregnancies, preterm birth, medical disorders in pregnancy, neurologic disorders in pregnancy, infectious disease in pregnancy

Education:

• B.Sc., 2000, University of Toronto, Canada
• MD, 2004, Western University, Canada
• Master of public health, 2008, Harvard University, U.S.
• Residency, 2009, obstetrics and gynecology, U of T
• Fellowship, 2012, maternal-fetal medicine, U of T

Appointments and Affiliations:

• Associate scientist, Evaluative Clinical Sciences, DAN Women & Babies Research Program, Sunnybrook Research Institute
• Staff physician, maternal-fetal medicine, Sunnybrook Health Sciences Centre
• Assistant professor, department of obstetrics and gynaecology, U of T

Research Foci:

• Obstetric interventions in preterm birth
• Substance use in pregnancy
• Maternal choice and counselling in complicated pregnancies

Research Summary:

The focus of Dr. Ladhani’s research is related to the improvement of care of women undergoing high-risk pregnancies. This includes the assessment of obstetric interventions to improve outcomes in preterm birth and to reduce the maternal and neonatal sequelae of preterm delivery. Current interests in this area include mode of delivery in extreme preterm gestations and maternal choice in the face of unanticipated pregnancy complications. Other areas of interest include optimization of care of women with a history of stillbirth and the care of women with stroke in pregnancy.  

Selected Publications:

See current publications list at PubMed.

1. Shea AK, Simpson AN, Barrett J, Ladhani N, Nevo O. Pregnancy outcomes of women admitted to a tertiary care centre with short cervix. J Obstet Gynaecol Can. 2017 May;39(5):328–34.
2. Fockler ME, Ladhani NNN, Watson J, Barrett JFR. Pregnancy subsequent to stillbirth: medical and psychosocial aspects of care. Semin Fetal Neonatal Med. 2017 Jun;22(3):186–92.
3. Lisonkova S, Mehrabadi A, Allen VM, Bujold E, Crane JM, Gaudet L, Gratton RJ, Ladhani NN, Olatunbosun OA, Joseph KS. Atonic postpartum hemorrhage: blood loss, risk factors, and third stage management. J Obstet Gynaecol Can. 2016 Dec;38(12):108–90.e2.
4. Siou K, Walmsley SL, Murphy KE, Raboud J, Loutfy M, Yudin MH, Silverman M, Ladhani NN, Serghides. Progesterone supplementation for HIV-positive pregnant women on protease inhibitor-based antiretroviral regimens (the ProSPAR study): a study protocol for a pilot randomized controlled trial. L. Pilot Feasibility Stud. 2016 Aug 12;2:49. eCollection 2016. Erratum in: Pilot Feasibility Stud. 2017 Apr 28;3:21.
5. Ladhani NN, Chitayat D, Nezarati MM, Laureane MC, Keating S, Silver RJ, Unger S, Velsher L, Sirkin W, Toi A, Glanc P. Dyssegmental dysplasia, Silverman-Handmaker type: prenatal ultrasound findings and molecular analysis. Prenat Diagn. 2013 Nov;33(11):1039–43.

Related News and Stories:

• Which interventions are best for extremely early preemies?: Studies seek to guide the care of babies born at the edge of viability (SRI Magazine, 2018)