Evaluative Clinical Sciences

Administrative Assistant: Antonella Iannaccio-Pesce
Phone: 416-480-5850
Email: antonella.iannaccio@sunnybrook.ca

Education:

• MD, 1996, Faculdade de Medicina da Fundacao do ABC, Brazil
• General surgery specialist, Faculdade de Medicina da Fundacao do ABC, Brazil
• Fellowship, 2008–2010, trauma surgery, University of Toronto, Canada
• Fellowship, 2010-2011, trauma and general surgery research, U of T, Canada
• Fellowship, 2011–2014, adult critical care medicine, U of T, Canada
• Fellowship, 2014–2016, acute are surgery, U of T, Canada
• M.Sc., 2015, catecholamines as outcome markers in traumatic brain injury: The COMA-TBI Study, U of T, Canada

Appointments and Affiliations:

• Associate scientist, Evaluative Clinical Sciences, Trauma Emergency & Critical Care Research Program, Sunnybrook Research Institute
• Staff general surgeon, Sunnybrook Health Sciences Centre
• Assistant professor, department of surgery, U of T

Research Summary:

Dr. da Luz's clinical research is focused on the early resuscitation phase of severely injured patients, with a special interest in severely bleeding trauma patients and management of early endogenous trauma coagulopathy. He is a member of Sunnybrook’s trauma research group, which has completed two randomized controlled trials, both addressing early resuscitation and hemostasis of patients with massive bleeding.

Dr. da Luz has special methodological interest in knowledge synthesis. He is currently conducting several systematic reviews and meta-analysis in surgery, trauma and critical care including:

• the use of fibrinogen concentrate and cryoprecipitate in trauma
• the perioperative use of thromboelastography and rotational thrombelastometry different surgical specialties
• outcomes post angioembolization of bleeding pelvic fractures
• field triage criteria and quality improvement initiatives in trauma
• fixed transfusion blood products ratios in bleeding trauma patients.

Selected Publications:
See current publications list at PubMed.

1. Da Luz LT, Marchand M, Nascimento B, Tien H, Nathens A, Shah P. Efficacy and safety of the drugs used to reverse direct oral anticoagulants: a systematic review and meta-analysis. Transfusion. 2017 Jul;57(7):1834–1846.
2. Rizoli SB, Jaja BN, Di Battista AP, Rhind SG, Neto AC, da Costa L, Inaba K, da Luz LT, Nascimento B, Perez A, Baker AJ, de Oliveira Manoel AL. Catecholamines as outcome markers in isolated traumatic brain injury: the COMA-TBI study. Crit Care. 2017 Feb 23;21(1):37.
3. Veigas PV, Callum J, Rizoli S, Nascimento B, Da Luz LT. A systematic review on the rotational thrombelastometry (ROTEM®) values for the diagnosis of coagulopathy, prediction and guidance of blood transfusion and prediction of mortality in trauma patients. Scand J Trauma Resusc Emerg Med. 2016;24(1):114.
4. Da Luz LT, Nascimento Junior B, Tien H. Current use of live tissue training in trauma: a descriptive systematic review-author response. Can J Surg. 2015; 58(6):E6–7.
5. Beckett A, Callum J, Da Luz LT, Schmid J, Funk C, Glassberg E, Tien H. Fresh whole blood transfusion capability for Special Operation Forces. Can J Surg. 2015;58(3):S153–156.
6. Da Luz LT, Nascimento B, Tien H, Kim MJ, Nathens AB, Vlachos S, Glassberg E. Current use of live tissue training in trauma: a descriptive systematic review. Can J Surg. 2015;58(3):S125–134.
7. Da Luz LT, Nascimento B, Sankarankutty A, Rizoli S, Adhikari NKJ. Effect of thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma: descriptive systematic review. Crit Care. 2014;18(5):518.
8. Da Luz LT, Nascimento B, Rizoli S. Thromboelastography (TEG®): practical considerations on its clinical use in trauma resuscitation. Scand J Trauma Resusc Emerg Med. 2013;21:29.
9. Luz Ld, Sankarankutty A, Passos E, Rizoli S, Fraga G, Nascimento B. Tranexamic acid for traumatic hemorrhage. Rev Col Bras Cir. 2012;39(1):77–80.
10. Sankarankutty AK, Luz LT, De Campos T, Rizoli S, Fraga G, Nascimento Jr B. Uncomplicated acute cholecystitis: early or delayed laparoscopic cholecystectomy? Rev Col Bras Cir. 2012;39(5):436–440.
11. Sankarankutty AK, Nascimento B, Da Luz LT, Rizoli S. TEG® and ROTEM® in trauma: similar tests but different results? World J Emerg Surg. 2012;7(1):S3.

Related Links:

Division of general surgery, U of T