Evaluative Clinical Sciences

Administrative Assistant: Afifa Siddiqui
Email: afifa.siddiqui@sunnybrook.ca

Education:

• H.B.Sc., 2006, integrative biology, University of Toronto, Canada
• MD, 2010, faculty of medicine, U of T, Canada
• Sc.M., 2014, health services research, Harvard School of Public Health, U.S.
• Fellowship, 2016, Royal College of Physicians and Surgeons of Ontario, Canada
• Clinician Investigator Program, 2016, Royal College of Physicians and Surgeons of Ontario, Canada
• Advanced fellowship, 2017, head and neck surgical oncology, and microvascular reconstruction, American Head and Neck Society, Ohio State University, U.S.

Appointments and Affiliations:

• Associate scientist, Evaluative Clinical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute
• Adjunct scientist, Institute for Clinical Evaluative Sciences (ICES), Cancer Research Program
• Associate professor, Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Toronto
• Assistant professor (Status only), Institute of Health Policy, Management and Evaluation (IHPME), Clinical Epidemiology and Health Care Research (CEHCR) Program, University of Toronto
• Head and neck surgical oncologist and reconstructive surgeon, Sunnybrook
• Chief of Otolaryngology – Head & Neck Surgery, Michael Garron Hospital
• Courtesy staff otolaryngologist, North York General Hospital, Women’s College Hospital and University Health Network

Research Foci:

• The management of mucosal head and neck cancers in Ontario with a focus on quality metrics
• Thyroid and parathyroid surgery outcomes in Ontario with a focus on structures of care that may impact outcomes
• The management of cancer patients during the COVID-19 pandemic, how this may have impacted outcomes and developing a roadmap for recovery
• Self-harm in cancer patients; The incidence, predictors and outcomes
• Integrated community health service centre development in Canada as a means to improve surgical wait times and outcomes

Research Summary:

Dr. Antoine Eskander is a head and neck oncologist and reconstructive surgeon at Sunnybrook Health Sciences Centre, Head and Neck Disease Site Lead at the Odette Cancer Centre, and Chief of Otolaryngology – Head & Neck Surgery at Michael Garron Hospital. He is an Associate Professor at the University of Toronto, Adjunct Scientist at ICES, and Associate Scientist at Sunnybrook Research Institute. He is also the current Lead and Chair of the Canadian Society of Otolaryngology – Head & Neck Surgery (CSOHNS) Collaborative Research Initiative and Research Lead for the Division of Head and Neck Surgical Oncology at the University of Toronto. Dr. Eskander is an internationally recognized researcher in the areas of head and neck cancers, health services research, clinical epidemiology, and quality improvement. He is interested in studying access to care, disparities in care, adherence to guidelines, volume-outcome associations, and quality metrics.

Academic Interests:

• Clinical Epidemiology
• Clinical Trials
• Head and Neck Oncology
• Endocrine Surgery (Thyroid and Parathyroid)
• Health Economics
• Health Outcomes Research
• Meta-Analysis
• Clinical Practice Guidelines
• Outcomes Research
• Quality Metrics

Professional and Clinical Interests:

• Clinical Research
• Endocrine Surgery
• Head & Neck Surgery
• Head and Neck Oncology
• Head and Neck Reconstruction
• Melanoma and Non-Melanoma Skin Cancer
• Microvascular and Free Tissue Transfer
• Parathyroid Disorders
• Salivary Gland Disease
• Thyroid Cancer
• Thyroid Surgery
• Transoral Robotic Surgery
• Thyroid Radiofrequency Ablation

Selected Publications:

See current publications list at PubMed.

1. Eskander A, Li Q, Yu J, Hallet J, Coburn NG, Dare A, Chan KKW, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Hanna TP, Finelli A, Louie AV, Look Hong N, Irish JC, Witterick IJ, Mahar A, Noel CW, Urbach DR, McIsaac DI, Enepekides D, Sutradhar R. Incident Cancer Detection During the COVID-19 Pandemic. J Natl Compr Canc Netw. 2022 Feb 1;20(3):276-284.
2. Noel CW, Sutradhar R, Zhao H, Delibasic V, Forner D, Irish JC, Kim J, Husain Z, Mahar A, Karam I, Enepekides DJ, Chan KKW, Singh S, Hallet J, Coburn NG, Eskander A. Patient-Reported Symptom Burden as a Predictor of Emergency Department Use and Unplanned Hospitalization in Head and Neck Cancer: A Longitudinal Population-Based Study. J Clin Oncol. 2021 Feb 20;39(6):675-684.
3. Hallet J, Sutradhar R, Isenberg-Grzeda E, Noel CW, Mahar AL, Vigod SN, Bolton J, Deleemans J, Chan WC, Coburn NG, Eskander A; Enhanced Supportive Psycho-oncology Canadian Care (ESPOC) Group. Association of Patient-Reported Outcomes With Subsequent Nonfatal Self-injury After a New Cancer Diagnosis. JAMA Oncol. 2022 May 1;8(5):e220203.
4. Eskander A, Noel CW, Griffiths R, Pasternak JD, Higgins K, Urbach D, Goldstein DP, Irish JC, Fu R. Surgeon Thyroidectomy Case Volume Impacts Disease-free Survival in the Management of Thyroid Cancer. Laryngoscope. 2023 May;133 Suppl 4:S1-S15.
5. Eskander A, Marqueen KE, Edwards HA, Joshua AM, Petrella TM, de Almeida JR, Goldstein DP, Ferket BS. To ban or not to ban tanning bed use for minors: A cost-effectiveness analysis from multiple US perspectives for invasive melanoma. Cancer. 2021 Jul 1;127(13):2333-2341.

Related News and Stories:

• Ontario-wide research atlas shows stable rates of head and neck cancers, except for rise in HPV-related throat cancer, ICES (Nov. 19, 2015)

Related Links:

• ICES profile
• Sunnybrook otolaryngology clinical profile
• U of T profile, department of otolaryngology–head & neck surgery