Odette Cancer Program

Administrative Assistant: Louise Tucker
Phone: 416-480-4998
Email: louise.tucker@sunnybrook.ca

Education:

• Eng. 2004, McGill University, Montreal, Quebec, Canada
• D., C.M., 2010, McGill University, Montreal, Quebec, Canada
• Postgraduate Residency, 2010-2015, Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada
• Research Fellow, 2015, MR-Guided Radiotherapy, Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
• Clinical Fellow, 2015-2016, Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada

Appointments and affiliations:

• Affiliate Scientist, Physical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute
• Radiation Oncologist and Clinician Investigator, Odette Cancer Centre, Sunnybrook Health Sciences Centre,
• Assistant Professor, Department of Radiation Oncology, University of Toronto

Research foci:

• Radiosurgery for brain metastases and primary central nervous system (CNS) malignancies
• Spine stereotactic body radiotherapy (SBRT)
• MR-guided radiotherapy/MR-Linac clinical applications
• Intact and post-operative prostate stereotactic body radiotherapy (SBRT)
• Prostate brachytherapy

Research summary:

Dr. Tseng has extensive interests in the application of novel technologies for the treatment of central nervous system (CNS) and genitourinary (GU) cancers. He is interested in image-guided, stereotactic radiotherapy of the spine, brain and GU neoplasms using conventional linear accelerators and Gamma Knife technology. In particular, he is investigating the neurocognitive impacts of brain irradiation in patients with multiple brain metastases. Given his technical background and training, he is involved in MR-guided radiotherapy/MR-Linac research, and its clinical applications including imaging-based biomarkers and individualized adaptive radiation.

Selected publications:

See current publications list at PubMed.

1. Alghamdi M, Sahgal A, Soliman H, Myrehaug S, Yang VXD, Das S, Wilson J, Campbell M, Lee YK, Cawricz M, DaCosta L, Atenafu EG, Tseng CL. Postoperative Stereotactic Body Radiotherapy for Spinal Metastases and the Impact of Epidural Disease Grade. Oxford University Press Dec 2019;85(6);E1111-E1118.
2. Raman R, Chin L, Erler D, Atenafu EG, Cheung P, Chu W, Chung H, Loblaw A, Poon I, Rubenstein J, Soliman H, Sahgal A, Tseng CL. Impact of magnetic resonance imaging on gross tumor volume delineation in non-spine bony metastasis treated with stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):735-43.e1.
3. Tseng CL, Soliman H, Myrehaug S, Lee YK, Ruschin M, Atenafu EG, Campbell M, Maralani P, Yang V, Yee A, Sahgal A. Imaging-based outcomes for 24 Gy in 2 daily fractions for patients with de novo spinal metastases treated with spine stereotactic body radiotherapy (SBRT). Int J Radiat Oncol Biol Phys. 2018;102(3):499-507.
4. Tseng CL, Eppinga W, Seravalli E, Hackett S, Brand E, Ruschin M, Lee YK, Atenafu EG, Sahgal A. Dosimetric feasibility of the hybrid magnetic resonance imaging (MRI)-linac system (MRL) for brain metastases: The impact of the magnetic field. Radiother Oncol. 2017;125(2):273-9.
5. Tseng CL, Sussman MS, Atenafu EG, Letourneau D, Ma L, Soliman H, Thibault I, Cho BC, Simeonov A, Yu E, Fehlings MG, Sahgal A. Magnetic resonance imaging assessment of spinal cord and cauda equina motion in supine patients with spinal metastases planned for spine stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys. 2015;91(5):995-1002.

Related links:

• U of T profile, Department of Radiation Oncology