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SRI Profiles

Tasnim Sinuff, MD, PhD, FRCPC


Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room D1 08
Toronto, ON
M4N 3M5

Phone: 416-480-6100, ext. 7694

Clinical ProfileShow/hide details

Executive Assistant: Meredith Malloy
Phone: 416-480-6100, ext. 2895


  • B.Sc., 1989, Biology, University of Winnipeg, Canada
  • MD, 1994, University of Alberta, Canada
  • FRCPC, 1997, Internal Medicine, McMaster University, Canada
  • FRCPC, 1999, Respirology, McMaster University, Canada
  • Royal College Credential, 2001, Critical Care, McMaster University, Canada
  • PhD, 2006, Health Research Methodology, McMaster University, Canada

Research ProfileShow/hide details

Appointments and Affiliations:

Research Foci:

  • Knowledge translation, guidelines and end-of-life issues in the intensive care unit

Research Summary:

Dr. Sinuff's primary area of research interest is knowledge translation in the intensive care unit (ICU). Her focus is on understanding behaviour change and guideline implementation in the ICU. She has a Canadian Institutes of Health Research Clinician Scientist Award to conduct her current research program, which involves knowledge translation in the ICU and a multifaceted approach to ventilator-associated pneumonia guideline implementation. This program will involve a combination of an observational cohort study, qualitative methods and a cluster-randomized controlled trial, and will examine a systematic approach to implementing and adhering to complex ventilator-associated pneumonia guidelines in the ICU.

Dr. Sinuff's secondary areas of research include the following:

  • End-of-life (EOL) issues in the ICU; and
  • Non-invasive ventilation for acute respiratory failure

In her end-of-life research, Dr. Sinuff's focus is family members' and patients' understanding of life support measures near and at the end of life and how ICU clinicians deal with EOL in order to improve our communication with patients and their families about life support measures and end-of-life care.

Dr. Sinuff's work in the area of non-invasive ventilation focuses on the following:

  • Summarizing the literature on the use noninvasive ventilation for acute respiratory failure;
  • Developing a comprehensive guideline for the use of noninvasive ventilation for patients with acute respiratory failure; and
  • Understanding the unique issues around implementation of technology guidelines

Selected Publications:

See current publications list at PubMed.

  1. Sinuff T, Patel R, Adhikari N, Meade M, Schuneman H, Cook DJ. Principal Author. Quality of Professional Society Guidelines and Consensus Conference Statements in Critical Care. Crit Care Med 2008; 36:1049–58.
  2. Sinuff T, Muscedere J, Cook DJ, Dodek P, Heyland DK. Principal Author. Ventilator Associate Pneumonia: Improving Outcomes Through Guideline Implementation. Journal of Crit Care 2008; 23:118–125.
  3. Sinuff T, Eva K, Meade, Dodek P, Heyland D, Cook DJ. Principal Author. Clinical Practice Guidelines in the ICU: A Canadian Survey. Can J Anaesthesia 2007 Sept; 54:728–736.
  4. Sinuff T, Cook DJ, Giacomini M, Heyland D, Dodek P. Principal Author. Facilitating Guideline Adherence in the ICU: A Qualitative Study. Crit Care Med 2007 Sept; 35:2085–2089.
  5. Sinuff T, Cook DJ, Giacomini M. Principal Author. How Qualitative Research can Contribute to Research in the ICU. J Crit Care 2007 Jun; 22(2):104–111.