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Evaluative Clinical Sciences

SRI Platforms

Dr. Jennifer Rabin

Scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room M6 178
Toronto, ON
M4N 3M5

Phone: 416-480-6100, ext. 83737

Education:

  • B.Sc., 2005, psychology, Dalhousie University, Canada
  • MA, 2009, clinical psychology (neuropsychology), York University, Canada
  • PhD, 2015, clinical psychology (neuropsychology), York University
  • Postdoctoral fellowship, 2018, Massachusetts General Hospital/Harvard Medical School, U.S.

Appointments and Affiliations:

Research Foci:

  • Neuromodulation
  • Neuropsychology
  • Alzheimer’s disease and related dementias
  • Vascular health

Research Summary:

Dr. Rabin’s research has two primary directions.

  1. As the Neuropsychology lead in the Harquail Centre for Neuromodulation, Dr. Rabin’s research characterizes cognitive, behavioural, and psychosocial changes associated with novel neuromodulation strategies. This includes low intensity focused ultrasound (FUS) to open up the blood brain barrier in patients with Alzheimer’s disease, and high intensity FUS to treat severe psychiatric and neurological conditions, such as depression, OCD, and tremor
  2. Another line of her research combines multi-modal neuroimaging (e.g., MRI, PET) with sensitive cognitive measures to better understand modifiable risk factors for Alzheimer’s disease and related dementias. Dr. Rabin was recently awarded a CIHR grant that will investigate risk factors for cognitive impairment in a multi-ethnic cohort, with a specific focus on cardiovascular risk factors and markers of cerebrovascular injury. This research is being carried out in close collaboration with Maged Goubran (co-PI), Sandra Black, and other colleagues at Sunnybrook.

Dr. Rabin is currently recruiting graduate students. Students can apply through one of two graduate programs at the University of Toronto:

  1. Clinical Psychology at UTSC, or
  2. Rehabilitation Sciences

If you are interested in applying, please contact Dr. Rabin at jennifer.rabin@sri.utoronto.ca.

Selected Publications:

See current publications list at PubMed.

  1. Rabin, JS, Davidson, B, Giacobbe, P, Hamani, C, Cohn, M, Illes, J, Lipsman, N. (2020). Neuromodulation for major depressive disorder: innovative measures to capture efficacy and outcomes. The Lancet Psychiatry. Epub ahead of print.
  2. Davidson, B, Hamani, C, Meng, Y, Baskaran, A, Sharma, S, Abrahao, A, Richter, MA, Levitt, A, Giacobbe, P, Lipsman, N, Rabin, JS. (2020). Examining cognitive change following magnetic resonance-guided focused ultrasound capsulotomy for psychiatric illness. Translational Psychiatry. Epub ahead of print.
  3. Rabin, JS*, Klein, H*, Kirn, DR, Schultz, AP, Yang, H-S, Hampton, O, Jiang, S, Buckley, RF, Viswanathan, A, Hedden, T, Pruzin, J, Yau, W-Y, Guzman-Velez, E, Quiroz, YT, Properzi, M, Marshall, GA, Rentz, DM, Johnson, KA, Sperling, RA, Chhatwal, JP. (2020). Physical activity moderates the association of amyloid burden on longitudinal cognitive decline and neurodegeneration. JAMA Neurology, 76(10), 1203-1210. *authors contributed equally
  4. Rabin, JS*, Yang, H-S*, Schultz, AP, Hanseeuw, BJ, Marshall, GA, Hedden, T, Kilpatrick, E, Klein, H, Buckley, RF, Properzi, MJ, Rao, V, Kirn, DR, Rentz, DM, Johnson, KA, Sperling, RA, Chhatwal, JP. (2019). Vascular risk and β-amyloid are synergistically associated with cortical tau. Annals of Neurology, 85, 272-279. *authors contributed equally
  5. Rabin, JS, Schultz, AP, Hedden, T, Viswanathan, A, Marshall, GA, Kilpatrick, E, Klein, H, Buckley, RF, Yang, H-S, Properzi, M, Rao, V, Kirn, DR, Papp, KV, Rentz, DM, Johnson, KA, Sperling, RA, Chhatwal, JP. (2018). Interactive associations of vascular risk and β-amyloid burden with cognitive decline in clinically normal elderly individuals: findings from the Harvard Aging Brain Study. JAMA Neurology, 75(9), 1124-1131

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