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Intraoperative imaging for therapeutic guidance in surgical resection and photodynamic therapy of glioblastoma

This project has resulted in a patent application describing a unique, low-cost, fluorescence-based imaging-guidance device for neurosurgery that was subsequently tested in a clinical demonstration trial at St. Michael’s Hospital. Intended for use during brain tumour surgery, for instance for glioblastoma multiform, where conventional total resection is difficult without injuring surrounding healthy tissue, this device may provide additional real-time imaging guidance that surgeons need to visualize better the tumour margin.