Magnetoencephalography and electroencephalography

Magnetoencephalography (MEG) and electroencephalography (EEG) are methods of studying human brain function noninvasively using extracranial (outside the brain) measurements of magnetic fields and electric potentials, respectively. These methods differ from functional MRI in that MEG and EEG are directly sensitive to neuronal activities and have a millisecond temporal resolution.

Our lab is developing MEG and EEG methods to understand better how the human brain works. Specific projects include MEG and EEG source localization, neuronal oscillations and integrating these imaging modalities with MRI.

Selected publications

Chang WT, Ahlfors SP, Lin FH. Sparse current source estimation using loose orientation constraint. Hum Brain Mapp. 2013 Sep;34(9):2190–2201.

Chang WT, Nummenmaa A, Hsieh JC, Lin FH. Spatially sparse source cluster modeling by compressive neuromagnetic tomography. Neuroimage. 2010 Oct 15;53(1):146–60.

Lin FH, Hara K, Solo V, Vangel M, Belliveau J, Stufflebeam S, Hämäläinen M. Dynamic Granger-Geweke causality modeling with application to interictal spike propagation. Hum Brain Mapp. 2009 Jun;30(6):1877–96.

Ahveninen J, Lin FH, Kivisaari R, Autti T, Hämäläinen M, Stufflebeam S, Belliveau JW, Kahkonen S. MRI-constrained spectral imaging of benzodiazepine modulation of spontaneous neuromagnetic activity in human cortex. Neuroimage. 2007 Apr 1;35(2):577–82.

Lin FH, Witzel T, Ahlfors SP, Stufflebeam SM, Belliveau JW, Hämäläinen MS. Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimates. Neuroimage. 2006 May 15;31(1):160–71.

Lin FH, Belliveau JW, Dale AM, Hämäläinen MS. Distributed current estimates with cortical orientation constraints. Hum Brain Mapp. 2006 Jan;27(1):1–13.