EXPRESS: Exercise as a primer for excitatory stimulation study

Mild cognitive impairment and Alzheimer's disease are conditions that involve memory difficulties. Transcranial direct current stimulation is a type of brain stimulation that emits low and constant electrical currents. It may help improve these memory difficulties; however, it works better on active brain areas. We want to see if combining exercise and applying currents to important parts of the brain can help improve memory in people with memory problems and mild cognitive impairment or Alzheimer's disease. We will also collect blood to see if this treatment can help with brain and blood vessel health, which we think is an important part of how this combination may work. A completely optional component of this study includes offering participants magnetic resonance imaging (MRI).