EXPRESS V: Exercise as a primer for excitatory stimulation study in vascular cognitive impairment no dementia (VCIND)

Individuals with vascular conditions are particularly at risk of having memory problems so we want to find effective treatments that can prevent further cognitive decline. In this study, we are using a non-invasive form of brain stimulation called transcranial direct current stimulation or tDCS. It involves placing small, square shaped pads or electrodes on the head. It has been shown to improve memory in patients with dementia, however, this brain stimulation may be most effective in patients at risk of memory decline due to vascular conditions. This brain stimulation is believed to work best when the brain is engaged. So, we hope to determine if exercise combined with tDCS can help improve memory performance compared to tDCS alone, exercise alone, or neither. A magnetic resonance imaging (MRI) scan will also be performed at screening and at the end of the study.