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Sunnybrook prostate cancer surgeon honored

June 18, 2014

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Sunnybrook surgical oncologist, Dr. Laurence Klotz, internationally-known for pioneering the Active Surveillance approach for men with low-risk prostate cancer has been awarded the prestigious Lister Prize from the University of Toronto's Department of Surgery for his ‘outstanding and continuing productivity of international stature, as evidenced by research publications, grants held, students trained and other evidence of stature of the work produced’. He has also been recently awarded The Society of Urologic Oncology Medal for making a significant and far-reaching impact in the field of urologic oncology.

A professor in the Department of Surgery at the University of Toronto, Dr. Klotz, led the multidisciplinary team at Sunnybrook, along with Drs. Richard Choo, Cyril Danjoux, Andrew Loblaw, and Danny Vesprini, who were the first to implement and report on a novel approach for patients with low risk prostate cancer based on initial expectations of management, with strategic intervention for the minority of patients who were diagnosed higher risk over time. This became known as Active Surveillance, a term coined by Dr. Klotz, with the emphasis on close monitoring and selective definitive intervention.

Findings from a 2010 Journal of Clinical Oncology-published study that he led, of 450 Canadian men with low-risk prostate cancer followed over 13 years, reported that patients managed with Active Surveillance with Selective Delayed Intervention had a 10-year prostate cancer actuarial survival of 97.2 per cent. Two thirds of patients avoided treatment entirely.

Dr. Laurence Klotz

Full media release

SUNNYBROOK CANCER SURGEON HONORED AS ACTIVE SURVEILLANCE LEADER

Toronto, CANADA (June 16, 2014) –Sunnybrook surgical oncologist, Dr. Laurence Klotz, internationally-known for pioneering the Active Surveillance approach for men with low-risk prostate cancer has been awarded the prestigious Lister Prize from the University of Toronto's Department of Surgery for his ‘outstanding and continuing productivity of international stature, as evidenced by research publications, grants held, students trained and other evidence of stature of the work produced’.

He has also been recently awarded The Society of Urologic Oncology Medal for making a significant and far-reaching impact in the field of urologic oncology.

A professor in the Department of Surgery at the University of Toronto, Dr. Klotz, led the multidisciplinary team at Sunnybrook, along with Drs. Richard Choo, Cyril Danjoux, Andrew Loblaw, and Danny Vesprini, who were the first to implement and report on a novel approach for patients with low risk prostate cancer based on initial expectations of management, with strategic intervention for the minority of patients who were diagnosed higher risk over time. This became known as Active Surveillance, a term coined by Dr. Klotz, with the emphasis on close monitoring and selective definitive intervention.

Dr. Klotz, also a member of the Genitourinary Cancer Care team at Sunnybrook’s Odette Cancer Centre continues to be a strong proponent of this approach to reduce overtreatment for patients, and is widely considered to have been instrumental in its acceptance by the urological community worldwide.

Findings from a 2010 Journal of Clinical Oncology-published study that he led, of 450 Canadian men with low-risk prostate cancer followed over 13 years, reported a resounding positive benefit. For patients managed with Active Surveillance with Selective Delayed Intervention, the 10-year prostate cancer actuarial survival was 97.2 per cent. Two thirds of patients avoided treatment entirely.

Active Surveillance with Selective Delayed Intervention is now a standard option for the first management of men with localized, well-differentiated prostate cancer, and is considered the treatment of choice for men with very low risk prostate cancer. The concept is increasingly being adopted in other cancer sites, particularly DCIS (ductal carcinoma in situ) for breast cancer.

For more information, please contact:

Natalie Chung-Sayers, 416.480-4040, natalie.chung-sayers@sunnybrook.ca

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