Odette Cancer Program

Administrative Assistant: Johnson Lee
Phone: 416-480-6100 x65765
Email: johnson.lee@sunnybrook.ca

Education:

• B.Sc., 2000, engineering physics, Queen’s University, Canada
• PhD, 2006, physics, Queen’s University, Canada

Appointments and Affiliations:

• Scientist, Physical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute
• Assistant professor, department of medical biophysics, University of Toronto

Research Foci:

• Medical imaging
• Micro-ultrasound
• Image-guided intervention
• Acoustic manipulation

Research Summary:

The primary focus of Dr. Démoré’s work is development of new ultrasound probes for a range of medical imaging applications. In particular, she is developing micro-ultrasound technologies for high-resolution images of tissues. By miniaturising these technologies, with probes integrated in endoscopes or needles, high-resolution visualisation of tissues deep within the body becomes possible, providing better guidance for interventional procedures and improved diagnostic information.

Dr. Démoré also investigates acoustic manipulation, also known as acoustic tweezing, of cells for biosciences research. She has developed arrays with independently controlled elements that generate reconfigurable ultrasound fields for trapping and moving particles and cells, useful for application including as cell sorting and tissue scaffolds.

Selected Publications:

See current publications list at PubMed.

1. Jiang Y, Qiu Z, McPhillips R, Meggs C, Mahboob SO, Wang H, Duncan R, Rodriguez Sanmartin D, Zhang Y, Schiavone G, Eisma R, Desmulliez MPY, Eljamel S, Cochran S, Button TW, Démoré CEM. Dual orientation 16-MHz single-element ultrasound needle transducers for image-guided neurosurgical intervention. IEEE Trans Ultrason Ferroelectr Freq Control. 2016 Feb;63(2):233–44.
2. Qiu Y, Gigliotti JV, Wallace M, Griggio F, Démoré CEM, Cochran S, Trolier-McKinstry S. Piezoelectric micromachined ultrasound transducer (PMUT) arrays for integrated sensing, actuation and imaging. Sensors. 2015 Apr 3;15(4):8020–41.
3. Démoré CEM, Dahl P, Yang Z, Glynne-Jones P, Melzer A, Cochran S, MacDonald MP, Spalding GC. Acoustic tractor beam. Phys Rev Lett. 2014 May 2;112(17):174302.
4. Démoré CEM, Yang Z, Volovick A, Cochran S, MacDonald MP, Spalding GC. Mechanical evidence of the orbital angular momentum to energy ratio of helical beams. Phys Rev Lett. 2012 May 11;108(19):194301.
5. Démoré CEM, Glynne-Jones P, Ye C, Qiu Y, Cochran S, Hill M. Array-controlled ultrasonic manipulation of particles in planar acoustic resonator. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Jun;59(6):1258–66.

Related News and Stories:

• Ultrasound research gets capital infusion: Two Sunnybrook Research Institute scientists receive federal and provincial infrastructure awards to further their work in image-guided therapeutics (May 22, 2018)
• Tool kit: DISCO DAD3240 high-precision dicing saw: High-precision saw used to engineer ultrasound imaging and therapy devices (Feb. 5, 2018)
• CV: Dr. Christine Démoré (Dec. 22, 2016)
• Good vibrations: SRI’s newest scientist gets a welcome homecoming after years abroad (Sept. 28, 2016)
• Star Trek-style ‘tractor beam’ created at university (BBC News, May 30, 2014)

Related Links:

• U of T profile, department of medical biophysics
• Centre for Research in Image-Guided Therapeutics
• Device Development Laboratory