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David Kreindler, B.Sc., MD, FRCPC

Associate scientist

Sunnybrook Health Sciences Centre
2075 Bayview Ave., Room FG 17
Toronto, ON
M4N 3M5

Phone: 416-480-5225
Fax: 416-480-6818

Administrative Assistant: Mae Dela Costa
Phone: 416-480-6030
Fax: 416-480-6818

Please note: Dr. Kreindler is not hiring summer students in 2024.


  • B.Sc., 1988, astronomy and physics, University of Toronto, Canada
  • MD, 1995, University of Cincinnati College of Medicine, U.S.

Appointments and Affiliations:

Research Foci:

Research Summary:

Dr. Kreindler’s primary research interest is the application of physics and cognitive science to psychiatry to understand better the origin of psychiatric illness – in particular, mood disorders. He has been working on characterizing mood dynamics, drawing on developments in nonlinear dynamics (Mainzer 1996), fractal geometry (Mandelbrot 1982), self-organized criticality (Bak 1996; Jensen 1998), and time series dynamics (Sardà-Espinosa, 2019) to illuminate the mechanisms that underpin mood. This approach is uniquely relevant to child and adolescent mood disorders as well as mood disorders across the rest of the lifespan since it approaches mood as a dynamic process embedded in time.

His other research interests are the application of information technology to clinical psychiatry, with specific interests in the use of technology for mood measurement. He maintains an active interest in data security issues as applied to clinical practice.

Selected Publications:

See current publications list at PubMed.

  1. Qian Y, Solano MJ, Kreindler D. Grouping of mood symptoms by time series dynamics. J Affect Disord. 2022 Jul 15;309:186-192. doi: 10.1016/j.jad.2022.04.117. Epub 2022 Apr 22. PMID: 35461820 
  2. Tang W, Kreindler D. Supporting Homework Compliance in Cognitive Behavioural Therapy: Essential Features of Mobile Apps. JMIR Ment Health. 2017 Jun 8;4(2):e20. doi: 10.2196/mental.5283. PMID: 28596145; PMCID: PMC5481663.
  3. Schaffer A, Kreindler D, Reis C, Levitt AJ. Use of mental health telemetry to enhance identification and predictive value of early changes during augmentation treatment for major depression. J Clin Psychopharmacol. 2013 Dec;33(6):775–81.
  4. Romans SE, Kreindler D, Asllani E, Einstein G, Laredo S, Levitt A, Morgan K, Petrovic M, Toner B, Stewart DE. Mood and the menstrual cycle. Psychother Psychosom. 2013;82(1):53–60.
  5. Manassis K, Mendlowitz S, Kreindler D, Lumsden C, Sharpe J, Simon MD, Woolridge N, Monga S, Adler-Nevo G. Mood assessment via animated characters: a novel instrument to evaluate feelings in young children with anxiety disorders. J Clin Child Adolesc Psychol. 2009 May;38(3):380–389. 
  6. Kreindler D. Email security in clinical practice: ensuring patient confidentiality. Open Medicine. 2008; 2(2):e54–59.
  7. Kreindler DM and Lumsden CJ. The effects of irregular sampling and missing data in time series analysis. Nonlinear Dynamics Psychol Life Sci. 2006 Apr; 10(2):187–214. 
  8. Kreindler D, Lumsden CJ, Levitt A, Woolridge N. Portable mood mapping: the validity and reliability of analog scale displays for mood assessment via hand held computer. Psychiatry Res. 2003 Sep; 120(2):165–177.

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