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Recent publications

Hodgson A, Amemiya Y, Seth A, Djordjevic B, Parra-Herran C. High-grade müllerian adenosarcoma: genomic and clinicopathologic characterization of a distinct neoplasm with prevalent TP53 pathway alterations and aggressive behavior. Am J Surg Pathol. 2017 Aug 22.

Hodgson A, Amemiya Y, Seth A, Cesari M, Djordjevic B, Parra-Herran C. Genomic abnormalities in invasive endocervical adenocarcinoma correlate with pattern ofinvasion: biologic and clinical implications. Mod Pathol. 2017 Jul 21.

Aguilar OA, Berry R, Rahim MM, Reichel JJ, Popović B, Tanaka M, Fu Z, Balaji GR, Lau TN, Tu MM, Kirkham CL, Mahmoud AB, Mesci A, Krmpotić A, Allan DS, Makrigiannis AP, Jonjić S, Rossjohn J, Carlyle JR. A viral immunoevasin controls innate immunity by targeting the prototypical natural killer cell receptor family. Cell. 2017 Mar 23;169(1):58–71.

Abdul-Wahid A, Cydzik M, Prodeus A, Alwash M, Stanojcic M, Thompson M, Huang EH, Shively JE, Gray-Owen SD, Gariépy J. Induction of antigen-specific TH 9 immunity accompanied by mast cell activation blocks tumor cell engraftment. Int J Cancer. 2016 Aug 15;139(4):841–53.

Nam RK, Benatar T, Wallis CJ, Amemiya Y, Yang W, Garbens A, Naeim M, Sherman C, Sugar L, Seth A. MiR-301a regulates E-cadherin expression and is predictive of prostate cancer recurrence. Prostate. 2016 Jul;76(10):869–84.

Klenov A, Neller KC, Burns LA, Krivdova G, Hudak KA. A small RNA targets pokeweed antiviral protein transcript. Physiol Plant. 2016 Mar;156(3):241–51.

Wallis CJ, Gordanpour A, Bendavid JS, Sugar L, Nam RK, Seth A. MiR-182 Is Associated with Growth, Migration and Invasion in Prostate Cancer via Suppression of FOXO1. J Cancer. 2015 Oct 25;6(12):1295–305.

Nam RK, Amemiya Y, Benatar T, Wallis CJ, Stojcic-Bendavid J, Bacopulos S, Sherman C, Sugar L, Naeim M, Yang W, Zhang A, Klotz LH, Narod SA, Seth A. Identification and validation of a five microRNA signature predictive of prostate cancer recurrence and metastasis: a cohort study. J Cancer. 2015 Sep 15;6(11):1160­–71.

Cydzik M, Abdul-Wahid A, Park S, Bourdeau A, Bowden K, Prodeus A, Kollara A, Brown TJ, Ringuette MJ, Gariépy J. Slow binding kinetics of secreted protein, acidic, rich in cysteine-VEGF interaction limit VEGF activation of VEGF receptor 2 and attenuate angiogenesis. FASEB J. 2015 Aug;29(8):3493–505.

Amemiya Y, Bacopulos S, Al-Shawarby M, Al-Tamimi D, Naser W, Ahmed A, Khalifa M, Slodkowska E, Seth A. A comparative analysis of breast and ovarian cancer-related gene mutations in Canadian and Saudi Arabian patients with breast cancer. Anticancer Res. 2015 May;35(5):2601–10.

Prodeus A, Abdul-Wahid A, Fischer NW, Huang EH, Cydzik M, Gariépy J. Targeting the PD-1/PD-L1 immune evasion axis with DNA aptamers as a novel therapeutic strategy for the treatment of disseminated cancers. Mol Ther Nucleic Acids. 2015 Apr 28;4:e237.

Allan DS, Kirkham CL, Aguilar OA, Qu LC, Chen P, Fine JH, Serra P, Awong G, Gommerman JL, Zúñiga-Pflücker JC, Carlyle JR. An in vitro model of innate lymphoid cell function and differentiation. Mucosal Immunol. 2015 Mar;8(2):340–51.

Wang T, Amemiya Y, Henry P, Seth A, Hanna W, Hsieh ET. Multiplex ligation-dependent probe amplification can clarify HER2 status in gastric cancers with "Polysomy 17". J Cancer. 2015 Feb 26;6(5):403–8.

Mulvaney JF, Amemiya Y, Freeman SD, Ladher RK, Dabdoub A. Molecular cloning and functional characterisation of chicken Atonal homologue 1: a comparison with human Atoh1. Biol Cell. 2015 Feb;107(2):41–60.

Sivanathan L, Chow A, Wong A, Hoang VC, Emmenegger U. In vivo passage of human prostate cancer cells in mice results in stable gene expression changes affecting numerous cancer-associated biological processes. Prostate. 2014 May;74(5):537–46.

Chatterjee S, Bacopulos S, Yang W, Amemiya Y, Spyropoulos D, Raouf A, Seth A. Loss of Igfbp7 causes precocious involution in lactating mouse mammary gland. PLoS One. 2014 Feb 4;9(2):e87858.

Huang X, Taeb S, Jahangiri S, Emmenegger U, Tran E, Bruce J, Mesci A, Korpela E, Vesprini D, Wong CS, Bristow RG, Liu FF, Liu SK. miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1. Cancer Res. 2013 Dec 1;73(23):6972–86.

Deng Z, Yang X, Fang L, Rutnam ZJ, Yang BB. Misprocessing and functional arrest of microRNAs by miR-Pirate: roles of miR-378 and miR-17. Biochem J. 2013 Mar 1;450(2):375­86.

Shan SW, Fang L, Shatseva T, Rutnam ZJ, Yang X, Du W, Lu WY, Xuan JW, Deng Z, Yang BB. Mature miR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7 and vimentin in different signal pathways. J Cell Sci. 2013 Mar 15;126(Pt 6):1517­–30.

Chow A, Amemiya Y, Sugar L, Nam R, Seth A. Whole-transcriptome analysis reveals established and novel associations with TMPRSS2:ERG fusion in prostate cancer. Anticancer Res. 2012 Sep;32(9):3629–41.

Buckley KM, Rast JP. Dynamic evolution of toll-like receptor multigene families in echinoderms. Front Immunol. 2012 Jun 5;3:136.


Academic director,
Professor Arun Seth, PhD
416-480-6100 ext. 63536
Room S2 38

Yutaka Amemiya, PhD

416-480-6100 ext. 63108
Room C7 50b

Sunnybrook Health Sciences Centre
2075 Bayview Avenue
Toronto, ON M4N 3M5